CD1D-B2M Heterodimer 蛋白, Human (HEK293, His)

The CD1D protein, a key antigen-presenting molecule, binds self and non-self glycolipids, presenting them to T-cell receptors on natural killer T-cells. Partnering with B2M, it centrally orchestrates immune responses, and its interactions with MHC II emphasize its significance in the intricate network of immune system regulation. CD1D-B2M Heterodimer Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived CD1D-B2M Heterodimer protein, expressed by HEK293 , with C-His labeled tag. CD1D-B2M Heterodimer Protein, Human (HEK293, His), has molecular weight of ~48 & 12 kDa, respectively.

CD1D-B2M 异二聚体蛋白是一种重要的抗原呈递分子，具有结合自身和非自身糖脂的独特能力，促进其呈递给自然杀伤 T 细胞上的 T 细胞受体。该蛋白质与 B2M（β-2-微球蛋白）形成异二聚体复合物，在协调免疫反应中发挥着核心作用。它与 MHC II 的相互作用进一步增强了它在复杂的免疫系统调节网络中的重要性。

Human

HEK293

C-His

P15813 (E20-S301)&P61769 (I21-M119)

912  [NCBI]&567  [NCBI]

EVPQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSNDSDTVRSLKPWSQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCEVHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKWTRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPGPGRLLLVCHVSGFYPKPVWVKWMRGEQEQQGTQPGDILPNADETWYLRATLDVVAGEAAGLSCRVKHSSLEGQDIVLYWGGSYTS&IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM

Approximately 48&12 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.