CD53 蛋白, Cynomolgus (HEK293, His)

CD53 protein is an important member of the tetraspanin family and plays an important role in immune response, cell adhesion and signal transduction. Its research enhances understanding of cell membrane organization and function, with potential applications in immunology and cancer research. CD53 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CD53 protein, expressed by HEK293 , with N-His labeled tag. The total length of CD53 Protein, Cynomolgus (HEK293, His) is 75 a.a., with molecular weight of 19-22 kDa.

CD53 蛋白是四跨膜蛋白 (TM4SF) 家族的重要成员，强调了其在细胞过程中的重要作用，包括免疫反应、细胞粘附和信号转导。作为该家族的一部分，CD53 可能与相关蛋白具有保守的结构和功能特征，强调其参与富含四跨膜蛋白的微结构域的形成以及与其他细胞分子的相互作用。四跨膜蛋白家族的分类强调了其在更广泛的膜蛋白背景下的特定名称，提供了对其对细胞膜组织和功能的独特贡献的见解。CD53 的研究有助于我们了解其在不同生理过程中的作用，提供在免疫学、癌症研究中的潜在应用，并更深入地理解其对细胞功能的更广泛影响。对 CD53 作用的进一步探索有望增强我们对其对正常生理和病理状况的贡献的了解。

Measured by its ability to inhibit chemoattract of Jurkat cell in presence of 40 ng/mL human CXCL12. At a concentration of 0.001 µg/mL, CD53 Protein, Cynomolgus(HEK 293, N-6His) effectively inhibits the chemotaxis of Jurkat cells.

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  Measured by its ability to inhibit chemoattract of Jurkat cell in presence of 40 ng/mL human CXCL12. At a concentration of 0.001 µg/mL, CD53 Protein, Cynomolgus（HEK 293, N-6His) effectively inhibits the chemotaxis of Jurkat cells.

Cynomolgus

HEK293

N-6*His

G7NW46 (E107-N181)

102127943  [NCBI]

EQKLNEYVAKGLTDSIHRYHSDNSTKAAWDSIQSFLQCCGINGTSDWTSGPPASCPSDPNVEGCYAKARLWFHSN

Approximately 17-23 kDa due to the glycosylation.

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.