1. 重组蛋白
  2. CD Antigens
  3. CD99L2 蛋白, Human (HEK293, His)

CD99L2 蛋白, Human (HEK293, His)

目录号: HY-P72697
产品使用指南

CD99L2 蛋白在晚期白细胞外渗中发挥关键作用,帮助细胞克服内皮基底膜。它与 PECAM1 在同一位点独立发挥作用,协调但独特地参与白细胞迁移的复杂过程。CD99L2 蛋白, Human (HEK293, His) 是重组的 CD99L2 蛋白,由 HEK293 表达,带有 C-6*His 标签。

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描述

The CD99L2 protein plays a critical role in late leukocyte extravasation, helping cells to overcome the endothelial basement membrane. It acts independently at the same site as PECAM1, coordinating but uniquely participating in the complex process of leukocyte migration. CD99L2 Protein, Human (HEK293, His) is the recombinant human-derived CD99L2 protein, expressed by HEK293 , with C-6*His labeled tag.

研究背景

CD99L2 在促进白细胞外渗的后期阶段发挥着至关重要的作用,帮助细胞克服内皮基底膜。它的作用与 PECAM1 发生在同一位点,尽管是独立的,这表明它对白细胞迁移的复杂过程有协调但独特的贡献。作为一种亲同性粘附分子,CD99L2 参与的相互作用虽然本质上是亲同性的,但对于细胞聚集可能不是必需的,这强调了其参与细胞粘附事件的复杂性。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

Q8TCZ2-1 (D26-A188)

基因 ID
蛋白结构
N-term
CD99L2 (D26-A188)
Accession # Q8TCZ2-1
6*His
C-term
同用名
CD99 Antigen-Like Protein 2; MIC2-Like Protein 1; CD99; CD99L2; MIC2L1
氨基酸序列

DFDDFNLEDAVKETSSVKQPWDHTTTTTTNRPGTTRAPAKPPGSGLDLADALDDQDDGRRKPGIGGRERWNHVTTTTKRPVTTRAPANTLGNDFDLADALDDRNDRDDGRRKPIAGGGGFSDKDLEDIVGGGEYKPDKGKGDGRYGSNDDPGSGMVAEPGTIA

分子量

25-55 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

CD99L2 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CD99L2 Protein, Human (HEK293, His)
目录号:
HY-P72697
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