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  4. CDR2 蛋白, Human (His)

CDR2 蛋白, Human (His)

目录号: HY-P72127
产品使用指南

CDR2蛋白是CDR2家族的成员。尽管所提供的参考段落中的描述有限，但 CDR2 蛋白主要与副肿瘤性神经系统疾病相关，特别是一种称为副肿瘤性小脑变性 (PCD) 的疾病。CDR2 蛋白, Human (His) 是重组的 CDR2 蛋白，由 E. coli 表达，带有 N-6*His 标签。CDR2 蛋白, Human (His) 全长 454 个氨基酸，分子量约为 ~55.9 kDa。

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规格 是否有货
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100 μg   询价  

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描述

CDR2 protein is a member of the CDR2 family. Although the description in the provided reference paragraph is limited, the CDR2 protein is primarily associated with paraneoplastic neurological diseases, specifically one called paraneoplastic cerebellar degeneration (PCD). CDR2 Protein, Human (His) is the recombinant human-derived CDR2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of CDR2 Protein, Human (His) is 454 a.a., with molecular weight of ~55.9 kDa.
研究背景

CDR2 蛋白是 CDR2 家族的成员。CDR2 蛋白主要与副肿瘤性神经系统疾病相关，特别是一种称为副肿瘤性小脑变性 (PCD) 的疾病。在 PCD 患者中，免疫系统错误地瞄准并攻击小脑，导致小脑功能丧失。CDR2 蛋白被认为是这个过程中的自身抗原，这意味着它会触发自身免疫反应。
种属

Human
表达系统

E. coli
标签

N-6*His
蛋白编号

Q01850 (M1-S454)
基因 ID
蛋白结构
N-term
6*His
CDR2 (M1-S454)
Accession # Q01850
C-term
同用名
AA617262; CDR 2; CDR 62; CDR2; CDR2_HUMAN; CDR62; Cerebellar degeneration related protein 2 62kDa; Cerebellar degeneration related protein 2; Cerebellar degeneration related protein; Cerebellar degeneration-related protein 2; Major Yo paraneoplastic antigen; MGC116181; MGC144810; MGC144811; Paraneoplastic cerebellar degeneration associated antigen; Paraneoplastic cerebellar degeneration-associated antigen; PCD 17; PCD17; RGD1310578; Yo; Yo paraneoplastic antigen
氨基酸序列

MLAENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSPTTPPEYKALFKEIFSCIKKTKQEIDEQRTKYRSLSSHS

分子量

Approximately 55.9 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

CDR2 Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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