CEACAM5 蛋白, Mouse (HEK293, His)

The CEACAM5 protein is a key cell surface glycoprotein that promotes cell adhesion, signaling, and tumor progression. It interacts with CEACAM6 and other related molecules to support homo- and hetero-sex adhesion. CEACAM5 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CEACAM5 protein, expressed by HEK293 , with C-His labeled tag.

CEACAM5 蛋白是一种细胞表面糖蛋白，在细胞粘附、细胞内信号传导和肿瘤进展中发挥着关键作用。它促进同性和异性细胞粘附，与其他癌胚抗原相关细胞粘附分子（特别是 CEACAM6）结合。作为癌基因，CEACAM5 通过诱导结直肠癌细胞对失巢凋亡的抵抗力来促进肿瘤进展。这种糖蛋白形成同二聚体，强调其在细胞相互作用和信号传导途径中作为多方面调节剂的作用，特别是影响与癌症发生和进展相关的过程。

Mouse

HEK293

C-His

Q3UKK2 (Q35-E947)

73250  [NCBI]

QITIELEPPQVIEGENVLIRVNNLTENLITLAWFRGMRIKSPQIGQYTPATKVTVLGPGHSGRETLYSNGSLQIYNVTQEDIGFYSLRIINKHAEIVSITSIYLNVYSSLWTCEHPSPHAKLTIESVPPGISEGGSVLLLVKNLPQNLLSLFWYKGVIAVKKFEIARHIKATNSSVPGPAHTGRETVFSNGSLLLQEVMQSDTGFYTLRTMSTDLKDEVAHVQLYMDTYLLTCYHPLQVKIESLPQNVAVGKTVLLLVHNLPEDFQAFFWYKSAYRRDTYKIAEYKRAMDATILGSAYSSREFIYNNGSMLIIDVTEDDAGYFLLEILREDLKIEKAYIQLHVNSFVSNSKDSASTARLSIESVPPSIVEGGSVLLLVHNLPKNLQSLFWYKGMIAEKKSELIQHIIATSSSLPGPAHSGRETVYNNGSLLLQRVMQNDTQFYTLQTMDTDLKYEVAHVQLQLDTSLSTWYHPLQVKIESLPRNVAVGKSVLFLVHNFPEVFRAFSWYKPAYKSHTSKIVEYHRFTDSATVGAAYRGIEVIFTNGSMVMIDVTEDDAGFYMLEILREDFKVEKAYVQLHVNSFVPNSKVSVSTARLSIESVPPSIVGGESVLLLVHNLPKNLQSLFWYKGVIAEEKSELIQHIIATSSSLPGPAHSGRETVYSNGSLLLQRVMQNDTGFYTLLTMSTDLKDEIAHVQLQLDTSTCCSLLTSDQLIIVPVPRNIAVGKSVLLLVCNVPKDVQTIFWYKSVYRTDIFKIAEYSRSMESTIWGLAHSGKEMVYTNGSLLIQNVTEHDAGLYMLEILHKDYKLERAHVQVHVNNPVSWPFVRVTDTTVRVQSSVVFTCFSADPGVSIRWLFNKQSLQLTERMTLSPSKCQLSIDPVWREDAGKYQCEVSNPVSSKSSLPVRLAVIEE

100-120 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized a 0.22 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4 or PBS, 6% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.