CEBPA 蛋白, Human (His)

CEBPA protein, also known as CCAAT/enhancer-binding protein α, is a transcription factor that plays a crucial role in regulating the expression of genes related to cell differentiation, proliferation, and metabolism. The reference paragraph states that CEBPA protein interacts with TAF1A and UBTF. CEBPA Protein, Human (His) is the recombinant human-derived CEBPA protein, expressed by E. coli , with N-His labeled tag. The total length of CEBPA Protein, Human (His) is 358 a.a., with molecular weight of ~44 kDa.

CEBPA蛋白，也称为CCAAT/增强子结合蛋白α，是一种转录因子，在调节细胞分化、增殖和代谢相关基因的表达中发挥着至关重要的作用。CEBPA 蛋白与 TAF1A 和 UBTF 相互作用。TAF1A 是通用转录因子 TFIID 的组成部分，对于转录起始至关重要。CEBPA 和 TAF1A 之间的相互作用表明 CEBPA 通过与 TFIID 复合物的结合可能参与转录活性的调节。另一方面，UBTF 是一种核仁蛋白，参与核糖体 RNA 转录和核糖体生物发生。CEBPA 和 UBTF 之间的相互作用暗示了 CEBPA 在调节这些过程中的潜在作用。需要进一步研究以充分了解这些相互作用的功能含义及其对 CEBPA 蛋白控制的细胞过程的贡献。

Human

E. coli

N-His

P49715-1 (M1-A358)

1050

MESADFYEAEPRPPMSSHLQSPPHAPSSAAFGFPRGAGPAQPPAPPAAPEPLGGICEHETSIDISAYIDPAAFNDEFLADLFQHSRQQEKAKAAVGPTGGGGGGDFDYPGAPAGPGGAVMPGGAHGPPPGYGCAAAGYLDGRLEPLYERVGAPALRPLVIKQEPREEDEAKQLALAGLFPYQPPPPPPPSHPHPHPPPAHLAAPHLQFQIAHCGQTTMHLQPGHPTPPPTPVPSPHPAPALGAAGLPGPGSALKGLGAAHPDLRASGGSGAGKAKKSVDKNSNEYRVRRERNNIAVRKSRDKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLRGIFRQLPESSLVKAMGNCA

Approximately 44 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from sterile 50 mM Tris-HCL, 300 mM NaCl, 200 mM arginine, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.