CEP57 蛋白, Human (His)

CEP57 is a centrosomal protein that is a potential player in promoting microtubule attachment to centrosomes, possibly by forming a ring-like structure around microtubules. The protein exhibits homodimer and homooligomer formation and interacts with microtubules. CEP57 Protein, Human (GST) is the recombinant human-derived CEP57 protein, expressed by E. coli , with N-GST labeled tag. The total length of CEP57 Protein, Human (GST) is 109 a.a., with molecular weight of 35-43 kDa.

CEP57（中心体蛋白 57）是一种中心体蛋白，可能通过在微管周围形成环状结构，在微管附着到中心体方面发挥潜在作用。它的参与延伸到介导内化生长因子 FGF2 的核转位和有丝分裂活性，从而将其相互作用与 FGF1 区别开来。CEP57 以同二聚体和同寡聚体形式存在，它与微管以及 FGF2 和 RAP80 相互作用。值得注意的是，它不表现出与 FGF1 或 FGF2 24 kDa 同工型的相互作用。这些特征表明 CEP57 在细胞过程中发挥多方面的作用，包括微管动力学和生长因子介导的信号通路的调节。它必须概述 CEP57 在微管附着、与生长因子相互作用及其寡聚性质方面的潜在功能。

Human

E. coli

N-6*His

Q86XR8 (S118-R226)

9702  [NCBI]

SKNEESKHNQELTSQLLAAENKCNLLEKQLEYMRNMIKHAEMERTSVLEKQVSLERERQHDQTHVQSQLEKLDLLEQEYNKLTTMQALAEKKMQELEAKLHEEEQERKR

Approximately 14 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.