CKMT2 蛋白, Rat (His, Solution)

CKMT2 Protein, predicted to have ubiquitin-protein transferase activity, is involved in regulating the epidermal growth factor receptor signaling pathway. It engages in autoubiquitination and ubiquitin-dependent protein catabolic processes via the multivesicular body sorting pathway. Positioned in the cytosol, CKMT2 demonstrates ubiquitous expression across tissues, emphasizing its involvement in diverse cellular processes and physiological functions throughout the body, with notable levels in the heart, fat, and 25 other tissues. CKMT2 Protein, Rat (His, Solution) is the recombinant rat-derived CKMT2 protein, expressed by E. coli , with N-His labeled tag. The total length of CKMT2 Protein, Rat (His, Solution) is 380 a.a., with molecular weight of ~47.0 kDa.

CKMT2 蛋白预计具有泛素蛋白转移酶活性，并通过多泡体分选途径参与表皮生长因子受体信号通路、蛋白自身泛素化和泛素依赖性蛋白分解代谢过程的负调节。预计该蛋白质位于细胞质中。值得注意的是，CKMT2 在各种组织中表现出普遍的表达，在心脏、脂肪和 25 种其他组织中观察到显着水平，表明它参与全身不同的细胞过程和生理功能。

Rat

E. coli

N-His

NP_001121124.1（D40-K419）

688698

DAREQHKLFPPSADYPDLRKHNNCMAECLTPTIYAKLRNKMTPSGYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKLRHNGYDPRVMKHPTDLDASKITHGQFDERYVLSSRVRTGRSIRGLSLPPACSRAERREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYILTCPSNLGTGLRAGVHVRIPKLSKDPRFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGRSEVELVQIVIDGVNYLVDCEKKLERGQDIKVPPPLPQFGRK

Approximately 47.0 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

溶液

Supplied as a 0.2 μm filtered solution of 50 mM Hepes, 750 mM NaCl, pH 6.0.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.