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  3. CKS2 蛋白, Human

CKS2 蛋白, Human

目录号: HY-P701662
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CKS2 蛋白与 TEK/TIE2 错综复杂地结合来调节 ANGPT1 信号传导。它的结合诱导受体酪氨酸磷酸化,影响下游细胞反应。CKS2 蛋白, Human 是重组的 CKS2 蛋白,由 E. coli 表达,不带标签。CKS2 蛋白, Human 全长 79 个氨基酸。

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描述

CKS2 protein intricately binds to TEK/TIE2 to regulate ANGPT1 signaling. Its binding induces receptor tyrosine phosphorylation, affecting downstream cellular responses. CKS2 Protein, Human is the recombinant human-derived CKS2 protein, expressed by E. coli , with tag free. The total length of CKS2 Protein, Human is 79 a.a., .

研究背景

血管生成素 4 (ANGPT4) 与 TEK/TIE2 错综复杂地结合,对 ANGPT1 信号传导发挥调控作用。它与 TEK/TIE2 的结合有可能诱导受体酪氨酸磷酸化,从而影响下游细胞反应。ANGPT4 在促进内皮细胞存活、增强细胞迁移和促进血管生成方面发挥着至关重要的作用,有助于血管过程的复杂协调。在结构上,ANGPT4 作为同二聚体存在,具有确保分子稳定性的二硫键。与 TEK/TIE2 的直接相互作用强调了 ANGPT4 在调节与血管稳态和血管生成反应相关的关键信号通路中的重要性。

种属

Human

表达系统

E. coli

标签

Tag Free

蛋白编号

P33552 (M1-K79)

基因 ID

1164

蛋白结构
N-term
CKS2 (M1-K79)
Accession # P33552
C-term
同用名
CKS2; Cyclin-dependent kinases regulatory subunit 2; CKS-2
纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

CKS2 Protein, Human 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

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Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CKS2 Protein, Human
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