CL-L1/COLEC10 蛋白, Cynomolgus (HEK293, Fc)

CL-L1/COLEC10, operating as a lectin, displays distinct sugar-binding preferences, with a hierarchy of galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine. Apart from its sugar-binding role, CL-L1/COLEC10 functions as a chemoattractant, suggesting potential engagement in the modulation of cell migration. CL-L1/COLEC10 Protein, Cynomolgus (HEK293, Fc) is the recombinant cynomolgus-derived CL-L1/COLEC10 protein, expressed by HEK293 , with N-hFc labeled tag.

CL-L1 (COLEC10) 是一种对多种糖具有高结合亲和力的凝集素蛋白，按以下顺序显示特异性：半乳糖 > 甘露糖 = 岩藻糖 > N-乙酰氨基葡萄糖 > N-乙酰半乳糖胺。作为一种凝集素，CL-L1 可能在糖识别和结合中发挥作用，其多样化的糖特异性表明其可能参与各种细胞过程。值得注意的是，CL-L1 充当化学引诱剂，这意味着可能在细胞迁移的调节中发挥作用。CL-L1 吸引细胞的能力表明它参与细胞运动的调节，可能影响免疫细胞运输或组织修复等过程。CL-L1 的糖结合特异性和化学引诱特性突出了其在介导细胞与其微环境之间的相互作用中的潜在重要性，强调了其在细胞反应和迁移调节中的作用（改编自所提供的通道）。

Immobilized beta-D-galactose at 10 µg/mL (100 µL/well) can bind Biotinylated Cynomolgus CL-L1 protein. The ED₅₀ for this effect is 1.130 μg/mL.

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  Immobilized beta-D-galactose at 10 µg/mL (100 µL/well) can bind Biotinylated Cynomolgus CL-L1 protein. The ED₅₀ for this effect is 1.130 μg/mL.

Cynomolgus

HEK293

N-hFc

XP_005564031.1 (G113-K277)

102117541  [NCBI]

GKAGTVCDCGRYRKFVGQLDISIARLKTSMKFVKNVIAGIRETEEKFYYIVQEEKNYRESLTHCRIRGGMLAMPKDEAANTLIADYVAKSGFFRVFIGVNDLEREGQYVFTDNTPLQNYSNWNEGEPSDPYGHEDCVEMLSSGRWNDTECHLTMYFVCEFIKKKK

Approximately 55-60 kDa due to the glycosylation.

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  Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4, 5% trehalose, 5% mannitol and 0.01% Tween80.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.