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  4. Claudin-11/CLDN11 蛋白, Human (HEK293, Fc)

Claudin-11/CLDN11 蛋白, Human (HEK293, Fc)

目录号: HY-P74250
产品使用指南

Claudin-11/CLDN11 蛋白在紧密连接的细胞间隙中发挥着至关重要的作用，这得益于其不依赖于钙的细胞粘附能力。与 tetraspanin-3/TSPAN3 的相互作用表明细胞过程中的潜在协作。CLDN11 与 OCLN 的关联凸显了它参与分子相互作用，有助于紧密连接的结构完整性和功能调节。Claudin-11/CLDN11 蛋白, Human (HEK293, Fc) 是重组的 Claudin-11/CLDN11 蛋白，由 HEK293 表达，带有 N-mFc 标签。Claudin-11/CLDN11 蛋白, Human (HEK293, Fc) 全长 60 个氨基酸，分子量约为 ~37 kDa。

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描述

Claudin-11/CLDN11 Protein plays a crucial role in tightly closing intercellular spaces in tight junctions, facilitated by its calcium-independent cell-adhesion capabilities. Interacting with tetraspanin-3/TSPAN3 suggests potential collaboration in cellular processes. CLDN11's associations with OCLN highlight its involvement in molecular interactions, contributing to the structural integrity and functional regulation of tight junctions. Claudin-11/CLDN11 Protein, Human (HEK293, Fc) is the recombinant human-derived Claudin-11/CLDN11 protein, expressed by HEK293 , with N-mFc labeled tag. The total length of Claudin-11/CLDN11 Protein, Human (HEK293, Fc) is 60 a.a., with molecular weight of ~37 kDa.
研究背景

Claudin-11 (CLDN11) 在紧密连接内细胞间隙的精确闭合中发挥着至关重要的作用，这主要得益于其不依赖于钙的细胞粘附能力。该蛋白还与 tetraspanin-3/TSPAN3 相互作用，表明在细胞过程中具有潜在的协同作用。此外，如实验结果所观察到的，CLDN11 与 OCLN 形成关联，阐明其参与分子相互作用，从而有助于紧密连接的结构完整性和功能调节。
种属

Human
表达系统

HEK293
标签

N-mFc
蛋白编号

O75508 (V23-R82)
基因 ID
蛋白结构
N-term
mFc
CLDN11 (V23-R82)
Accession # O75508
C-term
同用名
Claudin-11; CLDN11; OSP; OTM
分子量

Approximately 37 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

Claudin-11/CLDN11 Protein, Human (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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