CLEC12A/MICL 蛋白, Human (HEK293, His)

CLEC12A/MICL (C-type lectin domain family 12 member A/myelosuppressive C-type lectin-like receptor) is a cell surface receptor that acts as a modulator of signaling cascades, specifically promoting target MAP kinases Protease. CLEC12A/MICL Protein, Human (HEK293, His) is the recombinant human-derived CLEC12A/MICL protein, expressed by HEK293 , with N-His labeled tag.

CLEC12A/MICL（C 型凝集素结构域家族 12 成员 A/骨髓抑制性 C 型凝集素样受体）是一种细胞表面受体，可作为信号级联的调节器，特别促进目标 MAP 激酶的酪氨酸磷酸化。通过与 PTPN6 和 PTPN11 的相互作用，CLEC12A/MICL 参与了复杂的细胞信号传导过程，这表明它在调节免疫反应中具有重要意义，并有可能作为旨在操纵免疫系统功能的治疗干预的目标。

Human

HEK293

N-His

Q5QGZ9-1 (H75-A275)

160364  [NCBI]

40-45 kDa.

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.