CLEC5A/MDL-1 蛋白, Mouse (HEK293, Fc)

CLEC5A/MDL-1 Protein positively regulates osteoclastogenesis and acts as a cell surface receptor signaling via TYROBP. Its expression relies on the TYROBP interaction and it plays a role in regulating inflammatory responses. CLEC5A/TYROBP/HCST complex formation highlights its intricate involvement in immune and inflammatory processes. CLEC5A/MDL-1 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CLEC5A/MDL-1 protein, expressed by HEK293 , with N-hFc labeled tag.

CLEC5A/MDL-1 蛋白充当破骨细胞生成的正调节因子，并充当通过 TYROBP 发出信号的细胞表面受体。这种相互作用对于 CLEC5A 细胞表面表达至关重要。此外，该蛋白质在调节炎症反应中发挥作用。虽然以单体或同型二聚体形式存在，但大多数 CLEC5A 在巨噬细胞上以单体形式表达。它形成三分子复合物CLEC5A/TYROBP/HCST，主要依赖于TYROBP。与 TYROBP 和 HCST 的相互作用进一步强调了 CLEC5A 在免疫和炎症过程中的功能所涉及的复杂信号网络。

Mouse

HEK293

N-hFc

Q9R007-3 (Y26-K190)

23845  [NCBI]

64-68 kDa

Greater than 95% as determined by Tris-Bis PAGE.

无菌粉末

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.