1. 重组蛋白
  2. Receptor Proteins
  3. CMG-2/ANTXR2 蛋白, Human (HEK293, His)

CMG-2/ANTXR2 蛋白, Human (HEK293, His)

目录号: HY-P700656
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CMG-2/ANTXR2 蛋白作为炭疽毒素的受体,与 IV 型胶原蛋白和层粘连蛋白结合,表明其在细胞外基质粘附中的作用。基因突变与青少年透明纤维瘤病和婴儿系统性玻璃样变性有关。已发现多种同工型。它在多种组织中表达,包括前列腺和子宫内膜。CMG-2/ANTXR2 蛋白, Human (HEK293, His) 是重组的 CMG-2/ANTXR2 蛋白,由 HEK293 表达,带有 C-His 标签。

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描述

The CMG-2/ANTXR2 protein, acting as a receptor for anthrax toxin, binds to collagen IV and laminin, suggesting its role in extracellular matrix adhesion. Gene mutations are associated with juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple isoforms have been found. It is expressed in various tissues, including the prostate and endometrium. CMG-2/ANTXR2 Protein, Human (HEK293, His) is the recombinant human-derived CMG-2/ANTXR2 protein, expressed by HEK293 , with C-His labeled tag.

研究背景

CMG-2/ANTXR2 蛋白作为炭疽毒素的受体,并表现出与 IV 型胶原和层粘连蛋白的结合亲和力,表明其可能参与细胞外基质粘附。该基因的突变已被确定为青少年透明纤维瘤病和婴儿系统性玻璃样变病的原因。已发现该基因的几种编码不同亚型的转录变体。它在多种组织中显示出广泛的表达模式,包括前列腺、子宫内膜和 21 种其他组织。该信息由 RefSeq 截至 2009 年 3 月提供。

种属

Human

表达系统

HEK293

标签

C-His

蛋白编号

P58335-4/NP_477520.2 (Q34-G318)

基因 ID
蛋白结构
N-term
CMG-2 (Q34-G318)
Accession # P58335-4/NP_477520.2
His
C-term
同用名
Antxr2; HFS; cI-35; CMG-2; CMG2; ISH; JHF; JHS
分子量

38-43 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

CMG-2/ANTXR2 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CMG-2/ANTXR2 Protein, Human (HEK293, His)
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HY-P700656
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