1. 重组蛋白
  2. Enzymes & Regulators
  3. Hydrolases (EC 3)
  4. CNDP2 蛋白, Mouse (HEK293, His)

CNDP2 蛋白, Mouse (HEK293, His)

目录号: HY-P70103
产品使用指南

CNDP2 蛋白是一种酶,在肌肽和高肌肽的代谢中起着至关重要的作用。CNDP2 蛋白的失调与糖尿病肾病和神经退行性疾病有关。靶向 CNDP2 蛋白可能通过调节肌肽代谢、改善肾功能和潜在治疗这些疾病来提供潜在的治疗策略。CNDP2 蛋白, Mouse (HEK293, His) 是重组的 CNDP2 蛋白,由 HEK293 表达,带有 C-6*His 标签。CNDP2 蛋白, Mouse (HEK293, His) 全长 475 个氨基酸,分子量为 56-60 kDa。

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描述

CNDP2 Protein, an enzyme, plays a vital role in the metabolism of carnosine and homocarnosine. Dysregulation of CNDP2 Protein has been linked to diabetic nephropathy and neurodegenerative disorders. Targeting CNDP2 Protein may offer potential therapeutic strategies by regulating carnosine metabolism, improving renal function, and potentially treating these conditions. CNDP2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CNDP2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CNDP2 Protein, Mouse (HEK293, His) is 475 a.a., with molecular weight of 56-60 kDa.

研究背景

CNDP2蛋白在催化二肽、特别是苏氨酰二肽中的肽键水解方面表现出独特的功能。它在苏氨酰二肽的分解代谢中发挥组织特异性作用。此外,CNDP2 蛋白对半胱氨酰甘氨酸(谷胱甘肽代谢中的中间代谢产物)表现出显着的二肽酶活性。它还参与 N-乳酰氨基酸的代谢,通过水解它们形成乳酸和氨基酸,以及通过反向蛋白水解产生这些化合物。此外,CNDP2 蛋白有助于调节细胞周期停滞和细胞凋亡。

种属

Mouse

表达系统

HEK293

标签

C-6*His

蛋白编号

Q9D1A2 (M1-N475)

基因 ID
蛋白结构
N-term
CNDP2 (M1-N475)
Accession # Q9D1A2
6*His
C-term
同用名
rMuCytosolic non-specific dipeptidase/CNDP2, His; CNDP2; CNDP dipeptidase 2; Cytosolic non-specific dipeptidase; Glutamate carboxypeptidase-like protein 1; Cn2
氨基酸序列

MSALKAVFQYIDENQDRYVKKLAEWVAIQSVSAWPEKRGEIRRMMEVAAADVQRLGGSVELVDIGKQKLPDGSEIPLPPILLGKLGSDPQKKTVCIYGHLDVQPAALEDGWDSEPFTLVEREGKLYGRGSTDDKGPVAGWMNALEAYQKTGQEIPVNLRFCLEGMEESGSEGLDELIFAQKDKFFKDVDYVCISDNYWLGKNKPCITYGLRGICYFFIEVECSDKDLHSGVYGGSVHEAMTDLISLMGCLVDKKGKILIPGINDAVAPVTDEEHALYDHIDFDMEEFAKDVGAETLLHSCKKDILMHRWRYPSLSLHGIEGAFSGSGAKTVIPRKVVGKFSIRLVPDMIPEVVSEQVSSYLSKKFAELQSPNKFKVYMGHGGKPWVSDFNHPHYQAGRRALKTVFGVEPDLTREGGSIPVTLTFQEATGKNVMLLPVGSADDGAHSQNEKLNRLNYIEGTKMLAAYLYEVSQLKN

分子量

56-60 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

CNDP2 Protein, Mouse (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CNDP2 Protein, Mouse (HEK293, His)
目录号:
HY-P70103
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