Colicin-E1 蛋白, E.coli (Cell-Free, His, Myc)

Colicin-E1, a channel-forming colicin, serves as a transmembrane toxin inducing cytoplasmic membrane depolarization and cellular energy dissipation. It is part of a broader class of polypeptide toxins synthesized by and active against Escherichia coli and related bacterial strains. Colicin-E1 Protein, E.coli (Cell-Free, His, Myc) is the recombinant E. coli-derived Colicin-E1 protein, expressed by E. coli Cell-free , with N-10*His, C-Myc labeled tag. The total length of Colicin-E1 Protein, E.coli (Cell-Free, His, Myc) is 522 a.a., with molecular weight of 64.3 kDa.

Colicin-E1 是形成通道的大肠杆菌素的代表，作为一种跨膜毒素发挥作用，能够诱导细胞质膜去极化，导致细胞能量耗散。这些多肽毒素属于更广泛的大肠菌素类别，由大肠杆菌和密切相关的细菌菌株合成，并表现出针对大肠杆菌和密切相关的细菌菌株的活性。

E.coli

E. coli Cell-free

N-10*His;C-Myc

P02978 (M1-I522)

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METAVAYYKDGVPYDDKGQVIITLLNGTPDGSGSGGGGGKGGSKSESSAAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIVNEALRHNASRTPSATELAHANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGKRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINRINADITQIQKAISQVSNNRNAGIARVHEAEENLKKAQNNLLNSQIKDAVDATVSFYQTLTEKYGEKYSKMAQELADKSKGKKIGNVNEALAAFEKYKDVLNKKFSKADRDAIFNALASVKYDDWAKHLDQFAKYLKITGHVSFGYDVVSDILKIKDTGDWKPLFLTLEKKAADAGVSYVVALLFSLLAGTTLGIWGIAIVTGILCSYIDKNKLNTINEVLGI

66 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.