CRABP2 蛋白, Mouse (His)

CRABP2 is an important mediator that promotes intracellular retinoic acid transport and regulates its contact with nuclear retinoic acid receptors. This key role is essential for the cellular processes controlled by retinoic acid. CRABP2 Protein, Mouse (His) is the recombinant mouse-derived CRABP2 protein, expressed by E. coli , with N-His labeled tag. The total length of CRABP2 Protein, Mouse (His) is 137 a.a., with molecular weight of ~16 kDa.

CRABP2 是一种关键的细胞介质，在视黄酸的细胞内转运中发挥着关键作用，促进其转运至细胞核并调节其与核视黄酸受体的接触。这种转运机制是视黄酸控制的复杂细胞过程的核心。此外，CRABP2 参与细胞环境内的重要相互作用，与 importin α 形成复合物，这有助于其调节功能（通过相似性）。此外，CRABP2 与类视黄醇 X 受体 (RXR) 和视黄酸受体 α (RARA) 建立了重要的分子关联，强调了它参与复杂的核受体信号通路网络。这些相互作用共同强调了 CRABP2 在协调视黄酸动力学及其下游调节作用中的关键作用。

Mouse

E. coli

N-6*His

P22935 (P2-E138)

12904  [NCBI]

PNFSGNWKIIRSENFEEMLKALGVNMMMRKIAVAAASKPAVEIKQENDTFYIKTSTTVRTTEINFKIGEEFEEQTVDGRPCKSLVKWESGNKMVCEQRLLKGEGPKTSWSRELTNDGELILTMTADDVVCTRVYVRE

Approximately 16 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.