1. 重组蛋白
  2. Enzymes & Regulators
  3. Transferases (EC 2)
  4. CSNK2A1 蛋白, Human (His-SUMO)

CSNK2A1 蛋白, Human (His-SUMO)

目录号: HY-P700596
产品使用指南 技术支持

CK2α/CSNK2A1 蛋白能磷酸化丝氨酸或苏氨酸。它参与细胞周期、凋亡、转录和病毒感染的调控,对纺锤体组装检查点和 p53/TP53 介导的细胞凋亡有保护效应。CK2α/CSNK2A1 还能通过磷酸化各类因子参与信号传导,影响生物钟功能和病毒生命周期。CSNK2A1 蛋白, Human (His-SUMO) 是重组的 CSNK2A2 蛋白,由 E. coli 表达,带有 N-6*His 标签。

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描述

CK2α/CSNK2A1 protein can phosphorylate serine or threonine. It is involved in the regulation of cell cycle, apoptosis, transcription and viral infection, and has protective effects on the spindle assembly checkpoint and p53/TP53-mediated apoptosis. CK2α/CSNK2A1 can also participate in signal transduction by phosphorylating various factors, affecting circadian clock function and virus life cycle. CSNK2A1 Protein, Human (His-SUMO) is the recombinant human-derived CSNK2A1 protein, expressed by E. coli , with N-6*His labeled tag.

种属

Human

表达系统

E. coli

标签

N-SUMO;N-6*His

蛋白编号

P68400 (R8-N350)

基因 ID
蛋白结构
N-term
6*His
CSNK2A2 (R8-N350)
Accession # P68400
C-term
同用名
Casein kinase 2 alpha 1 polypeptide; Casein kinase II alpha 1; Casein kinase II alpha 1 subunit; Casein kinase II alpha subunit; Casein kinase II subunit alpha; CK II alpha; CK II; CK2 alpha; CK2 catalytic subunit alpha; CK2A1; CKII; CKIIalpha; CSK21_HUMAN; CSNK2A1
氨基酸序列

RARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVKDQARMGSSSMPGGSTPVSSAN

分子量

56.7 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

CSNK2A1 Protein, Human (His-SUMO) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CSNK2A1 Protein, Human (His-SUMO)
目录号:
HY-P700596
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