CCN2/CTGF 蛋白, Human (HEK293)

CCN2/CTGF (Connective Tissue Growth Factor) is a protein produced primarily by endothelial cells in blood vessels. It plays an important role in various cellular processes. CCN2/CTGF Protein, Human (HEK293) is the recombinant human-derived CCN2/CTGF protein, expressed by HEK293 , with tag free. The total length of CCN2/CTGF Protein, Human (HEK293) is 154 a.a., with molecular weight of ~21.15 kDa.

CCN2/CTGF（结缔组织生长因子）是一种主要由血管内皮细胞产生的蛋白质。它在各种细胞过程中发挥着重要作用。它的主要功能之一是吸引和刺激软骨细胞的增殖和分化，软骨细胞是参与软骨形成的细胞。此外，CCN2/CTGF 介导各种细胞类型的细胞粘附，包括成纤维细胞、肌成纤维细胞、内皮细胞和上皮细胞。这种粘附取决于肝素（一种多糖）和二价阳离子（例如钙或镁）的存在。此外，CCN2/CTGF 还能增强成纤维细胞生长因子（参与细胞生长和修复的蛋白质）诱导的 DNA 合成。总体而言，CCN2/CTGF 是一种重要的蛋白质，可调节软骨细胞功能、细胞粘附和 DNA 合成等细胞过程，有助于结缔组织的发育和维护。

Measured by its ability to mediate Balb/3T3 mouse embryonic fibroblast cell adhesion.The ED₅₀ this effect is 0.8781 μg/mL, corresponding to a specific activity is 1.139×10³ units/mg.

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  Measured by its ability to mediate Balb/3T3 mouse embryonic fibroblast cell adhesion.The ED₅₀ this effect is 0.8781 μg/mL, corresponding to a specific activity is 1.139×10³ units/mg.

Human

HEK293

Tag Free

Q5M8T4 (Q27-A180)

1490  [NCBI]

QNCSGPCRCPDEPAPRCPAGVSLVLDGCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRSGESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQTVVGPALA

Approximately 21.15 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 or 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.