2. 重组蛋白
  3. Cytokines and Growth Factors
  4. Chemokine & Receptors
  5. CXC Chemokines
  6. GRO-alpha
  7. GRO-alpha/CXCL1 蛋白, Mouse (His)

GRO-alpha/CXCL1 蛋白, Mouse (His)

目录号: HY-P700559
产品使用指南

GRO-alpha (CXCL1) 蛋白具有趋化特性，可在炎症反应期间吸引并激活中性粒细胞。这种血液调节趋化因子还抑制造血祖细胞增殖，强调其在造血调节中的复杂作用。截短形式KC(5-72)在体外表现出显着增强的造血活性。GRO-alpha/CXCL1 蛋白, Mouse (His) 是重组的 GRO-alpha/CXCL1 蛋白，由 E. coli 表达，带有 N-6*His 标签。GRO-alpha/CXCL1 蛋白, Mouse (His) 全长 68 个氨基酸，分子量为 11.5 kDa。

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100 μg   询价  

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描述

GRO-alpha (CXCL1) Protein, with chemotactic properties, attracts and activates neutrophils during inflammatory responses. This hematoregulatory chemokine also suppresses hematopoietic progenitor cell proliferation, emphasizing its intricate role in hematopoiesis regulation. The truncated form KC(5-72) notably exhibits significantly enhanced hematopoietic activity in vitro. GRO-alpha/CXCL1 Protein, Mouse (His) is the recombinant mouse-derived GRO-alpha/CXCL1 protein, expressed by E. coli , with N-6*His labeled tag. The total length of GRO-alpha/CXCL1 Protein, Mouse (His) is 68 a.a., with molecular weight of 11.5 kDa.
研究背景

GRO-alpha (CXCL1) 蛋白具有趋化特性，可吸引中性粒细胞并在炎症反应期间促进其激活。此外，这种血液调节趋化因子显示出抑制造血祖细胞增殖的能力，突出了其在调节造血中的复杂作用。值得注意的是，截短形式的KC(5-72)在体外表现出显着增强的造血活性。
种属

Mouse
表达系统

E. coli
标签

N-6*His
蛋白编号

P12850 (N29-K96)
基因 ID
蛋白结构
N-term
6*His
CXCL1 (N29-K96)
Accession # P12850
C-term
同用名
Growth-Regulated Alpha Protein; C-X-C Motif Chemokine 1; GRO-Alpha(1-73); Melanoma Growth Stimulatory Activity; MGSA; Neutrophil-Activating Protein 3; NAP-3; CXCL1; GRO; GRO1; GROA; MGSA; SCYB1
氨基酸序列

NELRCQCLQTMAGIHLKNIQSLKVLPSGPHCTQTEVIATLKNGREACLDPEAPLVQKIVQKMLKGVPK

分子量

11.5 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

GRO-alpha/CXCL1 Protein, Mouse (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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