1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Chemokine & Receptors
  4. CXC Chemokines
  5. CXCL17
  6. CXCL17 蛋白, Rat

CXCL17 蛋白, Rat

目录号: HY-P71897
COA 产品使用指南

C-X-C基序趋化因子配体17是趋化因子家族成员,在肿瘤发生中具有致病和保护作用。CXCL17 蛋白, Rat 是重组的 CXCL17 蛋白,由 E. coli 表达,不带标签。CXCL17 蛋白, Rat 全长 97 个氨基酸,分子量约为 ~11.5 kDa。

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规格 价格 是否有货 数量
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2 μg ¥350 In-stock
10 μg ¥850 In-stock
50 μg ¥2400 In-stock
100 μg ¥4000 In-stock
> 100 μg   询价  

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

C-X-C motif chemokine ligand 17 is the chemokine family member, and has a causative and protective effect in tumorigenesis. CXCL17 Protein, Rat is the recombinant rat-derived CXCL17 protein, expressed by E. coli , with tag free. The total length of CXCL17 Protein, Rat is 97 a.a., with molecular weight of ~11.5 kDa.

研究背景

C-X-C motif chemokine ligand 17 是一种黏膜趋化因子,可将未成熟的树突状细胞和血液单核细胞吸引到肺部。C-X-C motif chemokine ligand 17 通过血管生成活性促进肿瘤发生。C-X-C motif chemokine ligand 17 对大肠杆菌、金黄色葡萄球菌、沙门菌、铜绿假单胞菌和白色念珠菌具有较强的抗菌活性[1][2][3][4][5]

生物活性

Fully biologically active when compared to standard. The ED50 as determined by its ability to induce VEGF expression using murine endothelial cells is less than 5.0 μg/mL, corresponding to a specific activity of >200 IU/mg

种属

Rat

表达系统

E. coli

标签

Tag Free

蛋白编号

D4A875 (S23-L119)

基因 ID

308436  [NCBI]

蛋白结构
N-term
CXCL17 (S23-L119)
Accession # D4A875
C-term
中文名
重组鼠CXCL17蛋白
同用名
C-X-C motif chemokine ligand 17; CXCL17
氨基酸序列

SPNQEVARHHGDQHQAPRRWLWEGGQECDCKDWSLRVSKRKTTAVLEPPRKQCPCDHVKGSEKKNRRQKHHRKSQRPSRTCQQFLKRCQLASFTLPL

分子量

Approximately 11.5 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

性状

无菌粉末

组分

Lyophilized from a 0.2 μm solution of 50 mM Tris-HCL, 300 mM NaCl, pH 8.0.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in sterile distilled water. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
CXCL17 Protein, Rat
目录号:
HY-P71897
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