1. 重组蛋白
  2. Ubiquitin Related Proteins
  3. DCAF7 蛋白, Human (Sf9)

DCAF7 蛋白, Human (Sf9)

目录号: HY-P701521
产品使用指南

DCAF7蛋白在颅面发育中占据中心地位,对于EDN1通路和上颌骨形成至关重要。其细微的参与表明第一和第二拱门对 EDN1 功能的不同要求。DCAF7 蛋白, Human (Sf9) 是重组的 DCAF7 蛋白,由 Sf9 insect cells 表达,不带标签。DCAF7 蛋白, Human (Sf9) 全长 341 个氨基酸。

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描述

The DCAF7 protein occupies a central position in craniofacial development and is critical for the EDN1 pathway and maxillary formation. Its nuanced involvement suggests different requirements for EDN1 function in the first and second arches. DCAF7 Protein, Human (Sf9) is the recombinant human-derived DCAF7 protein, expressed by Sf9 insect cells , with tag free. The total length of DCAF7 Protein, Human (Sf9) is 341 a.a., .

研究背景

DCAF7 蛋白在颅面发育中占据中心地位,在 EDN1 通路上游发挥关键作用,并对上颌等效物(腭方骨)的形成做出显着贡献。第一和第二拱门中 EDN1 通路功能的不同活性要求凸显了其微妙的参与。此外,DCAF7 与 DIAPH1 形成复杂的伙伴关系,对 GLI1 转录活性进行控制。除了颅面发育之外,这种蛋白质在正常和疾病相关的皮肤发育中也发挥着潜在的作用。值得注意的是,它可能作为 CUL4-DDB1 E3 泛素-蛋白质连接酶复合物的底物受体发挥作用,揭示其参与蛋白质修饰过程,特别是蛋白质泛素化。

种属

Human

表达系统

Sf9 insect cells

标签

Tag Free

蛋白编号

P61962 (S2-V342)

基因 ID

10238

蛋白结构
N-term
DCAF7 (S2-V342)
Accession # P61962
C-term
同用名
DCAF7; DDB1- and CUL4-associated factor 7; WD repeat-containing protein 68; WD repeat-containing protein An11 homolog
纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

DCAF7 Protein, Human (Sf9) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
DCAF7 Protein, Human (Sf9)
目录号:
HY-P701521
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