2. 重组蛋白
  3. CD Antigens
  4. Dendritic Cell CD Proteins
  5. DEC-205/CD205
  6. DEC-205/CD205 蛋白, Cynomolgus (HEK293, His)

DEC-205/CD205 蛋白, Cynomolgus (HEK293, His)

目录号: HY-P701022
产品使用指南

DEC-205/CD205 蛋白是一种内吞受体，可将捕获的抗原转运至专门的处理室，将其置于抗原呈递的最前沿。这一作用对于免疫监视和启动免疫反应至关重要。DEC-205/CD205 的参与还可下调 B 淋巴细胞增殖，显示其对免疫细胞动态和反应的调节影响。DEC-205/CD205 蛋白, Cynomolgus (HEK293, His) 是重组的 DEC-205/CD205 蛋白，由 HEK293 表达，带有 C-His 标签。DEC-205/CD205 蛋白, Cynomolgus (HEK293, His) 全长 1639 个氨基酸，分子量为 230-245 kDa。

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3.  试用装只面向终端客户。

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描述

DEC-205/CD205 Protein, an endocytic receptor, transports captured antigens to a specialized processing compartment, placing it at the forefront of antigen presentation. This role is crucial for immune surveillance and initiating immune responses. DEC-205/CD205's involvement also downregulates B-lymphocyte proliferation, showcasing its regulatory impact on immune cell dynamics and responses. DEC-205/CD205 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived DEC-205/CD205 protein, expressed by HEK293 , with C-His labeled tag. The total length of DEC-205/CD205 Protein, Cynomolgus (HEK293, His) is 1639 a.a., with molecular weight of 230-245 kDa.
研究背景

DEC-205/CD205 蛋白作为内吞受体，促进捕获的抗原从细胞外空间运输到专门的抗原处理室。这一功能使 DEC-205/CD205 处于抗原呈递的最前沿，在免疫监视和免疫反应的启动中发挥着至关重要的作用。此外，它的参与导致 B 淋巴细胞增殖下调，突出了它对免疫细胞动力学和反应的调节影响。
种属

Cynomolgus
表达系统

HEK293
标签

C-His
蛋白编号

XP_005573337.2 (S28-D1666)
基因 ID
蛋白结构
N-term
CD205 (S28-D1666)
Accession # XP_005573337.2
His
C-term
同用名
Ly-75; DEC-205; CD205; CLEC13B; GP200-MR6; LY75
分子量

230-245 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

DEC-205/CD205 Protein, Cynomolgus (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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