1. 重组蛋白
  2. Immune Checkpoint Proteins CD Antigens Biotinylated Proteins
  3. Stimulatory Immune Checkpoint Molecules NK Cell CD Proteins Platelet CD Proteins
  4. DNAM-1/CD226 DNAM-1/CD226
  5. DNAM-1 蛋白, Human (HEK293, His-Avi)

DNAM-1 蛋白, Human (HEK293, His-Avi)

目录号: HY-P78429
产品使用指南

DNAM-1 蛋白在细胞间粘附和淋巴细胞信号传导中发挥关键作用,介导 CTL 和 NK 细胞的细胞毒性和淋巴因子分泌。作为 NECTIN2 的受体,DNAM-1 在配体结合后刺激 T 细胞增殖和细胞因子产生(IL2、IL5、IL10、IL13 和 IFNG)。DNAM-1 蛋白, Human (HEK293, His-Avi) 是重组的 DNAM-1 蛋白,由 HEK293 表达,带有 C-Avi, C-His 标签。DNAM-1 蛋白, Human (HEK293, His-Avi) 全长 229 个氨基酸,分子量为 45-70 kDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

DNAM-1 protein is a key player in cell-cell adhesion and lymphocyte signaling, mediating cytotoxicity and lymphokine secretion of CTL and NK cells. As a receptor for NECTIN2, DNAM-1 stimulates T cell proliferation and cytokine production (IL2, IL5, IL10, IL13, and IFNG) upon ligand binding. DNAM-1 Protein, Human (HEK293, His-Avi) is the recombinant human-derived DNAM-1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of DNAM-1 Protein, Human (HEK293, His-Avi) is 229 a.a., with molecular weight of 45-70 kDa.

研究背景

DNAM-1 蛋白与细胞毒性 T 淋巴细胞 (CTL) 和自然杀伤 (NK) 细胞介导的细胞间粘附、淋巴细胞信号传导、细胞毒性和淋巴因子分泌密切相关。DNAM-1 作为 NECTIN2 的细胞表面受体,在与配体结合后,刺激 T 细胞增殖和细胞因子(如 IL2、IL5、IL10、IL13 和 IFNG)的产生。此外,DNAM-1 与 PVRIG 竞争 NECTIN2 结合,强调了其在细胞相互作用和信号通路中的调节作用。该蛋白还与 PVR 和 NECTIN2 相互作用,有助于其在免疫反应和细胞通讯中的多方面功能。

种属

Human

表达系统

HEK293

标签

C-Avi;C-His

蛋白编号

Q15762 (E19-N247)

基因 ID
蛋白结构
N-term
DNAM-1 (E19-N247)
Accession # Q15762
His-Avi
C-term
同用名
CD226 molecule; CD226; DNAM1; PTA1; TLiSA1
分子量

45-70 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

DNAM-1 Protein, Human (HEK293, His-Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
DNAM-1 Protein, Human (HEK293, His-Avi)
目录号:
HY-P78429
需求量: