1. 重组蛋白
  2. Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. Cadherins
  5. Desmocollin-2
  6. DSC2/Desmocollin-2 蛋白, Rat (HEK293, Fc)

DSC2/Desmocollin-2 蛋白, Rat (HEK293, Fc)

目录号: HY-P76302
产品使用指南

DSC2(或 Desmocollin-2)是细胞间桥粒连接的重要组成部分,在斑块蛋白和中间丝之间的复杂相互作用网络中发挥着关键作用。在这些连接处,DSC2 有助于细胞间粘附,促进组织的凝聚力和稳定性。DSC2/Desmocollin-2 蛋白, Rat (HEK293, Fc) 是重组的 DSC2/Desmocollin-2 蛋白,由 HEK293 表达,带有 C-hFc 标签。DSC2/Desmocollin-2 蛋白, Rat (HEK293, Fc) 全长 666 个氨基酸,分子量约为 ~101.6 KDa。

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     可免费申领三个不同产品的试用装。

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描述

DSC2 (or Desmocollin-2) is an important component of desmosome connections between cells and plays a key role in the complex interaction network between plaque proteins and intermediate filaments. At these junctions, DSC2 contributes to cell-cell adhesion, promoting tissue cohesion and stability. DSC2/Desmocollin-2 Protein, Rat (HEK293, Fc) is the recombinant rat-derived DSC2/Desmocollin-2 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of DSC2/Desmocollin-2 Protein, Rat (HEK293, Fc) is 666 a.a., with molecular weight of ~101.6 KDa.

研究背景

Desmocollin-2 (DSC2) 是细胞间桥粒连接的重要组成部分,在细胞间粘附中发挥着关键作用。作为桥粒的一部分,DSC2 有助于介导细胞间相互作用的复杂网络。这些连接对于维持组织完整性至关重要,并通过斑块蛋白和中间丝的相互作用提供结构支持。DSC2 参与该分子复合物强调了其在确保组织(尤其是承受机械应力的组织)的内聚力和稳定性方面的重要性。该蛋白质促进细胞间粘附的功能凸显了其在维持组织结构和整体细胞完整性中的重要性。(参考:提供的资料)

种属

Rat

表达系统

HEK293

标签

C-hFc

蛋白编号

Q3T1K6 (C29-P694)

基因 ID
蛋白结构
N-term
DSC2 (C29-P694)
Accession # Q3T1K6
hFc
C-term
同用名
Cadherin family member 2; CDHF2; DSC3; Desmosomal glycoprotein II
分子量

Approximately 101.6 kDa.

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

DSC2/Desmocollin-2 Protein, Rat (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
DSC2/Desmocollin-2 Protein, Rat (HEK293, Fc)
目录号:
HY-P76302
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