DSG2/Desmoglein-2 蛋白, Mouse (HEK293, His)

DSG2/Desmoglein-2 proteins mediate cell-cell adhesion by interacting with plaque proteins and intermediate filaments at desmosome junctions. It plays a vital role in desmosome structure, maintaining tissue integrity and cohesion. DSG2/Desmoglein-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived DSG2/Desmoglein-2 protein, expressed by HEK293 , with C-His labeled tag.

DSG-2 是细胞间桥粒连接的关键成分，通过参与斑块蛋白和中间丝之间的相互作用，在介导细胞间粘附方面发挥着关键作用。这种桥粒结构的整体参与强调了其在维持组织完整性和内聚力方面的重要性。值得注意的是，DSG-2 在桥粒复合物内形成重要的连接，有助于细胞间粘附的稳健性。此外，它与 PKP2 的相互作用进一步强调了复杂的分子网络，该网络协调细胞连接中桥粒的稳定性和功能。

Mouse

HEK293

C-His

O55111 (A55-A618)

13511  [NCBI]

75-80 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.