1. 重组蛋白
  2. Enzymes & Regulators Ubiquitin Related Proteins
  3. Transferases (EC 2) Ubiquitin Enzymes
  4. E3 Ligases
  5. DTX3 蛋白, Human

DTX3 蛋白, Human

目录号: HY-P701522
产品使用指南

DTX3 蛋白是 Notch 信号传导的多功能调节因子,可调节细胞间通讯和细胞命运决定。其作用是依赖于环境的,根据发育和细胞环境表现出积极和消极的调节。DTX3 蛋白, Human 是重组的 DTX3 蛋白,由 E. coli 表达,不带标签。DTX3 蛋白, Human 全长 346 个氨基酸。

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描述

The DTX3 protein is a multifunctional regulator of Notch signaling that regulates intercellular communication and cell fate decisions. Its effects are context-dependent, exhibiting positive and negative regulation depending on the developmental and cellular environment. DTX3 Protein, Human is the recombinant human-derived DTX3 protein, expressed by E. coli , with tag free. The total length of DTX3 Protein, Human is 346 a.a., .

研究背景

DTX3 作为 Notch 信号传导复杂领域中的多功能调节剂而出现,Notch 信号传导是协调细胞间通信和管理多种细胞命运决定的关键途径。它的作用似乎与环境相关,对 Notch 信号传导发挥积极和消极的调节作用,具体取决于特定的发育和细胞环境。DTX3 的功能多功能性延伸到其作为体外泛素连接酶蛋白的能力,表明它可能参与 Notch 通路内泛素介导的调节机制。这种双重功能强调了 DTX3 在微调 Notch 信号动力学方面的复杂性和适应性,有助于控制细胞命运决定的复杂调控网络。

种属

Human

表达系统

E. coli

标签

Tag Free

蛋白编号

Q8N9I9 (S2-D347)

基因 ID

196403

蛋白结构
N-term
DTX3 (S2-D347)
Accession # Q8N9I9
C-term
同用名
DTX3; Probable E3 ubiquitin-protein ligase DTX3; Protein deltex-3; Deltex3; RING finger protein 154; RING-type E3 ubiquitin transferase DTX3
纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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DTX3 Protein, Human
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HY-P701522
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