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  3. ELAVL3 蛋白, Human (P.pastoris, His)

ELAVL3 蛋白, Human (P.pastoris, His)

目录号: HY-P71819
产品使用指南

ELAVL3 蛋白是一种 RNA 结合蛋白,可特异性结合靶 mRNA(包括 VEGF)中的 ARE 序列。它还可能通过其 RRM3 与 polyA 束相互作用。ELAVL3 蛋白, Human (P.pastoris, His) 是重组的 ELAVL3 蛋白,由 P. pastoris 表达,带有 N-His 标签。ELAVL3 蛋白, Human (P.pastoris, His) 全长 367 个氨基酸,分子量约为 ~41.5 kDa。

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描述

ELAVL3 protein is an RNA-binding protein that specifically binds to the ARE sequence in target mRNA, including VEGF. It may also interact with polyA tracts through its RRM3. ELAVL3 Protein, Human (P.pastoris, His) is the recombinant human-derived ELAVL3 protein, expressed by P. pastoris , with N-His labeled tag. The total length of ELAVL3 Protein, Human (P.pastoris, His) is 367 a.a., with molecular weight of ~41.5 kDa.

研究背景

ELAVL3 蛋白作为一种 RNA 结合蛋白,特异性结合靶 mRNA(包括 VEGF mRNA)内富含 AU 的元件 (ARE) 序列。此外,它可能通过其第三个 RNA 识别基序 (RRM3) 与聚 A 束相互作用。ELAVL3 在神经元分化和维持中发挥潜在作用,表明它参与神经系统内的基本过程。此外,它在 GAP43 mRNA 的稳定中发挥作用,并有助于空间学习。该蛋白的功能范围延伸到与 MAP1B 轻链 LC1 的相互作用,进一步强调了它参与与 RNA 调节以及与神经元功能和学习相关的细胞过程相关的复杂分子网络。

种属

Human

表达系统

P. pastoris

标签

N-His

蛋白编号

Q14576 (M1-A367)

基因 ID
蛋白结构
N-term
His
ELAVL3 (M1-A367)
Accession # Q14576
C-term
同用名
ELAV like 3; ELAV like 4; ELAV like neuron specific RNA binding protein 3; ELAV like neuron specific RNA binding protein 4; ELAV like protein 3; ELAV like protein 4; ELAV-like protein 3; PLE21; PNEM
氨基酸序列

MVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKSPLSLIARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA

分子量

Approximately 41.5 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

ELAVL3 Protein, Human (P.pastoris, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
ELAVL3 Protein, Human (P.pastoris, His)
目录号:
HY-P71819
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