2. 重组蛋白
  3. Cytokines and Growth Factors Receptor Proteins Enzymes & Regulators
  4. Ephrin/Eph Family Receptor Tyrosine Kinases Protein Tyrosine Kinases
  5. Eph Receptors
  6. EphA1
  7. EphA1 蛋白, Human (sf9, His, GST)

EphA1 蛋白, Human (sf9, His, GST)

目录号: HY-P702706
产品使用指南 技术支持

EphA1 蛋白是一种受体酪氨酸激酶，与膜结合的肝配蛋白 A 配体参与双向信号传导。EFNA1 的激活可调节细胞附着、运动、血管生成和增殖。EphA1 也可能在细胞凋亡中发挥作用。EphA1 蛋白, Human (sf9, His, GST) 是重组的 EphA1 蛋白，由 Sf9 insect cells 表达，带有 His, GST 标签。EphA1 蛋白, Human (sf9, His, GST) 全长 409 个氨基酸

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描述

EphA1 Protein, a receptor tyrosine kinase, engages in bidirectional signaling with membrane-bound ephrin-A ligands. Activation by EFNA1 regulates cell attachment, motility, angiogenesis, and proliferation. EphA1 may also play a role in apoptosis. EphA1 Protein, Human (sf9, His, GST) is the recombinant human-derived EphA1, expressed by Sf9 insect cells , with His, GST labeled tag. The total length of EphA1 Protein, Human (sf9, His, GST) is 409 a.a.,
研究背景

EphA1 蛋白是一种受体酪氨酸激酶，与邻近细胞上膜结合的肝配蛋白 A 配体相互作用，产生接触依赖性双向信号传导。该受体介导正向信号传导和反向信号传导途径。其高亲和力配体 EFNA1 的激活可调节各种细胞过程，包括细胞附着、运动、血管生成和增殖。此外，EphA1 可能在细胞凋亡中发挥作用。
种属

Human
表达系统

Sf9 insect cells
标签

His;GST
蛋白编号

P21709-1 (F568-D976)
基因 ID

2041
同用名
EPHA1; Eph receptor A1; ephrin type-A receptor 1; mEpha1; embryonic stem cell kinase; tyrosine-protein kinase receptor ESK; Eph; Esk; AL033318; 5730453L17Rik
纯度

Greater than 80 % as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

EphA1 Protein, Human (sf9, His, GST) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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