EPHA10 蛋白, Cynomolgus (HEK293, His)

EphA10, a receptor for ephrin-A family members, selectively binds EFNA3, EFNA4, and EFNA5, indicating its involvement in mediating cellular responses to ephrin-A ligands and participating in diverse cellular processes regulated by Eph-ephrin signaling pathways. EPHA10 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived EPHA10 protein, expressed by HEK293 , with C-His labeled tag. The total length of EPHA10 Protein, Cynomolgus (HEK293, His) is 532 a.a., with molecular weight of 68-80 kDa.

EphA10 被确定为肝配蛋白 A 家族成员的受体，在细胞信号传导中发挥着至关重要的作用。具体来说，它充当肝配蛋白配体 EFNA3、EFNA4 和 EFNA5 的受体。EphA10 和这些肝配蛋白 A 家族成员之间的相互作用表明它参与多种细胞过程，可能包括细胞间通讯和组织发育的调节。这种受体-配体结合能力凸显了 EphA10 在介导信号事件中的重要性，这些信号事件有助于各种生理和发育过程。

Measured by its binding ability in a functional ELISA. When Cynomolgus EPHA10 is coated at 5 μg/mL (100 μL/well) can bind Human Ephrin-A3. The ED₅₀ for this effect is 1.106 ng/mL.

Cynomolgus

HEK293

C-6*His

XP_045230088.1 (E34-A565)

102120465  [NCBI]

EEVILLDSKASQAELGWTALPSNGWEEISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLAAFPATAAESAFSTLVEVAGTCVAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDICEACPPGFYKVSPRRPLCSPCPEHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLALRLRWLPPADSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFVPRQAGLRERAATLLHLRPGARYTVRVAALNGVSGPAAAAGATYAQVTVSTGPGAPWEEDEIRRERVEPQSVSLSWREPIPAGAPGANGTEYEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEAQSFNPSIEVQTPGEAASGSRDQSPA

Approximately 68-80 kDa due to the glycosylation.

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of PBS, pH 8.0, 8% trehalose.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.