1. 重组蛋白
  2. Cytokines and Growth Factors Receptor Proteins Enzymes & Regulators
  3. Ephrin/Eph Family Receptor Tyrosine Kinases Protein Tyrosine Kinases
  4. Eph Receptors
  5. EphB2
  6. EphB2 蛋白, Mouse (HEK293, His)

EphB2 蛋白, Mouse (HEK293, His)

目录号: HY-P75235
产品使用指南

EphB2 蛋白是一种受体酪氨酸激酶,可与相邻细胞上的跨膜肝配蛋白 B 配体结合,启动双向信号传导。正向信号源自受体,而反向信号源自肝配蛋白配体。EphB2 蛋白, Mouse (HEK293, His) 是重组的 EphB2 蛋白,由 HEK293 表达,带有 C-His 标签。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The EphB2 protein is a receptor tyrosine kinase that binds to the transmembrane ephrin B ligand on adjacent cells to initiate bidirectional signaling. The forward signal originates from the receptor, while the reverse signal originates from the ephrin ligand. EphB2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived EphB2 protein, expressed by HEK293 , with C-His labeled tag.

研究背景

EphB2 蛋白是一种受体酪氨酸激酶,与相邻细胞上的跨膜肝配蛋白 B 家族配体混杂结合,启动接触依赖性双向信号传导。源自受体的下游途径称为正向信号传导,而肝配蛋白配体下游的信号传导途径称为反向信号传导。EphB2 在发育过程中的轴突引导中发挥着重要作用,特别是在引导形成大脑皮层两个颞叶之间主要半球间连接的连合轴突方面。此外,它还参与在中线引导对侧内耳传出生长锥,并将视网膜神经节细胞轴突引导至视盘。除了轴突引导作用之外,EphB2 还调节树突棘的发育和成熟,并刺激兴奋性突触的形成。EFNB1 的激活消除了 ARHGEF15 介导的对兴奋性突触形成的负调节。EphB2 通过调节内淋巴的产生来控制发育的各个方面,包括血管生成、上颚发育和内耳发育。EFNB2/EPHB2 复合物通过正向和反向信号传导,调节使尿道管状化和分隔泄殖腔的细胞的运动和粘附。此外,EphB2可能作为肿瘤抑制因子发挥作用,并参与血小板活化和凝血的调节。

种属

Mouse

表达系统

HEK293

标签

C-His

蛋白编号

P54763-3 (V19-K540)

基因 ID
蛋白结构
N-term
EphB2 (V19-K540)
Accession # P54763-3
His
C-term
同用名
EPHB2; Ephrin type-B receptor 2; EK5; DRT; EPHT3; ERK; HEK5; TYRO5
分子量

Approximately 65 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
EphB2 Protein, Mouse (HEK293, His)
目录号:
HY-P75235
需求量: