2. 重组蛋白
  3. Cytokines and Growth Factors Receptor Proteins Enzymes & Regulators Biotinylated Proteins
  4. Ephrin/Eph Family Receptor Tyrosine Kinases Protein Tyrosine Kinases
  5. Eph Receptors
  6. EphB4
  7. EphB4 蛋白, Human (Biotinylated, HEK293, His)

EphB4 蛋白, Human (Biotinylated, HEK293, His)

目录号: HY-P77545
产品使用指南

EphB4 蛋白是一种受体酪氨酸激酶，可与肝配蛋白 B 配体结合并启动双向信号传导。正信号传导调节细胞与表达 EFNB2 的细胞的排斥和分离。EphB4 蛋白, Human (Biotinylated, HEK293, His) 是重组的 EphB4 蛋白，由 HEK293 表达，带有 C-His 标签。

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100 μg   询价  

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描述

EphB4 protein is a receptor tyrosine kinase that binds to ephrin B ligand and initiates bidirectional signaling. Positive signaling regulates the rejection and separation of cells from EFNB2-expressing cells. EphB4 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived EphB4 protein, expressed by HEK293 , with C-His labeled tag.
研究背景

EphB4 蛋白是一种受体酪氨酸激酶，与位于相邻细胞上的跨膜肝配蛋白 B 家族配体混杂结合，启动接触依赖性双向信号传导。源自受体的下游途径称为正向信号传导，而肝配蛋白配体下游的信号传导途径称为反向信号传导。EphB4 与其同源配体 EFNB2 合作，复杂地参与调节细胞粘附和迁移。此外，EphB4 在心脏形态发生、血管生成以及血管重塑和通透性中发挥着核心作用。EPHB4 介导的正向信号传导有助于控制细胞排斥和与表达 EFNB2 的细胞的分离。
种属

Human
表达系统

HEK293
标签

C-His
蛋白编号

P54760-1/NP_004435.3 (L16-A539)
基因 ID
蛋白结构
N-term
EphB4 (L16-A539)
Accession # P54760-1/NP_004435.3
His
C-term
同用名
Ephrin type-B receptor 4; EPHB4; HTK; MYK1; TYRO11
分子量

Approximately 58.5 kDa.
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

EphB4 Protein, Human (Biotinylated, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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