ERMAP 蛋白, Human (HEK293, His)

ERMAP protein potentially serves as a cell-adhesion or receptor molecule in erythroid cells, suggesting involvement in crucial interactions or signaling events. The precise mechanisms, ligands, and broader implications of ERMAP's activity in erythroid cell biology require further investigation. Unraveling ERMAP's function may provide insights into its significance in hematopoiesis and related physiological processes. ERMAP Protein, Human (HEK293, His) is the recombinant human-derived ERMAP protein, expressed by HEK293 , with C-6*His labeled tag.

ERMAP 蛋白表现出作为细胞粘附或受体分子的潜在作用，特别是在红系细胞中。这意味着它参与介导对红细胞功能至关重要的相互作用或信号事件。ERMAP 介导的细胞粘附或受体活性的精确机制和配体，以及其在红细胞生物学中的更广泛的影响，值得进一步研究。解开 ERMAP 在红系细胞中的复杂功能可能有助于阐明其在造血和相关生理过程中的重要性。

Measured by its ability to inhibit anti-CD3 antibody induced IL-2 by Jurkat cells. The ED₅₀ for this effect is 1.485 μg/mL. Corresponding to a specific activity is 673.401 U/mg.

Human

HEK293

C-6*His

Q96PL5 (H30-A155)

114625  [NCBI]

HAGDAGKFHVALLGGTAELLCPLSLWPGTVPKEVRWLRSPFPQRSQAVHIFRDGKDQDEDLMPEYKGRTVLVRDAQEGSVTLQILDVRLEDQGSYRCLIQVGNLSKEDTVILQVAAPSVGSLSPSA

Approximately 16-17 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4 or PBS, pH 7.4, 5% trehalose, 5% mannitol and 0.01% Tween80 or PBS, pH 7.4, 8% trehalose.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.