1. 重组蛋白
  2. CD Antigens Fc Receptors
  3. Macrophage CD Proteins Monocyte CD Proteins Platelet CD Proteins Dendritic Cell CD Proteins Fc-gamma Receptor
  4. Fc gamma RII/CD32 FCGR2A/CD32a
  5. FCGR2A/CD32a
  6. Fc gamma RIIA/CD32a 蛋白, Human (CHO, His)

Fc gamma RIIA/CD32a 蛋白, Human (CHO, His)

目录号: HY-P76230
产品使用指南

Fc gamma RIIA/CD32a 蛋白作为低亲和力受体发挥着关键作用,可特异性结合免疫球蛋白 gamma 的 Fc 区。它与 IgG 相互作用,启动针对病原体的细胞反应,这对于免疫调节至关重要。Fc gamma RIIA/CD32a 蛋白, Human (CHO, His) 是重组的 Fc gamma RIIA/CD32a 蛋白,由 CHO 表达,带有 C-His 标签。

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描述

Fc gamma The RIIA/CD32a protein plays a key role as a low-affinity receptor that specifically binds to the Fc region of immunoglobulin gamma. It interacts with IgG to initiate cellular responses against pathogens, which is critical for immune regulation. Fc gamma RIIA/CD32a Protein, Human (CHO, His) is the recombinant human-derived Fc gamma RIIA/CD32a protein, expressed by CHO , with C-His labeled tag.

研究背景

Fc γ RIIA/CD32a 蛋白通过特异性结合免疫球蛋白 γ 的 Fc 区而发挥关键作用,充当低亲和力受体。通过与 IgG 相互作用,Fc gamma RIIA/CD32a 启动针对病原体和可溶性抗原的细胞反应,说明其在免疫调节中的重要作用。值得注意的是,该蛋白质促进调理抗原的吞噬作用,进一步促进免疫防御机制。此外,Fc gamma RIIA/CD32a 与 IGHG1、INPP5D/SHIP1、INPPL1/SHIP2、APCS、FGR 和 HCK 相互作用,表明其参与复杂的信号传导途径及其细胞功能的调节。这些多方面的相互作用强调了 Fc gamma RIIA/CD32a 在协调不同免疫反应中的重要性。

种属

Human

表达系统

CHO

标签

C-His

蛋白编号

P12318-1 (Q34-I218, H167)

基因 ID
蛋白结构
N-term
CD32a (Q34-I218, H167)
Accession # P12318-1
His
C-term
同用名
FCGR2A; CD32; CD32A; CDw32; IGFR2; fcRII-a; fc-gamma-RIIa; FCG2; FcGR; FCGR2; FCGR2A1; MGC23887; MGC30032
分子量

29-32 kDa.

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Fc gamma RIIA/CD32a Protein, Human (CHO, His)
目录号:
HY-P76230
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