1. 重组蛋白
  2. Cytokines and Growth Factors
  3. FGF Family
  4. FGFR1OP 蛋白, Human (sf9, His-GST)

FGFR1OP 蛋白, Human (sf9, His-GST)

目录号: HY-P76927
产品使用指南

FGFR1OP 对于微管动力学至关重要,将微管锚定在中心体上,这对于细胞组织至关重要。它在纤毛形成中发挥着不可或缺的作用,有助于控制纤毛形成的复杂过程。FGFR1OP 蛋白, Human (sf9, His-GST) 是重组的 FGFR1OP 蛋白,由 Sf9 insect cells 表达,带有 N-His, N-GST 标签。FGFR1OP 蛋白, Human (sf9, His-GST) 全长 378 个氨基酸,分子量约为 ~69 kDa。

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描述

FGFR1OP is critical for microtubule dynamics, anchoring microtubules at centrosomes, which is critical for cell organization. It plays an integral role in cilia formation and helps control the complex process of cilia formation. FGFR1OP Protein, Human (sf9, His-GST) is the recombinant human-derived FGFR1OP protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag. The total length of FGFR1OP Protein, Human (sf9, His-GST) is 378 a.a., with molecular weight of ~69 kDa.

研究背景

FGFR1OP 作为将微管锚定到中心体的重要因素,在微管动力学中发挥着至关重要的作用,强调了它在细胞组织中的重要性。此外,FGFR1OP 对于纤毛是不可或缺的,有助于控制细胞纤毛形成和维持的复杂过程。在结构上,FGFR1OP 形成同型二聚体,并且与 CEP350 和 MAPRE1 一起构成三元复合物,突显其参与对中心体和微管相关功能至关重要的分子相互作用。FGFR1OP 与 CEP350 和 MAPRE1 的直接相互作用强调了其在协调细胞结构组装和组织中的作用。此外,FGFR1OP 与 CEP19 结合,进一步扩展其相互作用网络并暗示其参与各种细胞过程。

种属

Human

表达系统

Sf9 insect cells

标签

N-His;N-GST

蛋白编号

O95684-2 (A2-A379)

基因 ID
蛋白结构
N-term
His-GST
FGFR1OP (A2-A379)
Accession # O95684-2
C-term
同用名
Centrosomal protein 43; FGFR1 oncogene partner; CEP43; FOP
分子量

Approximately 69 kDa

纯度

Greater than 85% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

FGFR1OP Protein, Human (sf9, His-GST) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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FGFR1OP Protein, Human (sf9, His-GST)
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HY-P76927
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