1. 重组蛋白
  2. Enzymes & Regulators
  3. Transferases (EC 2)
  4. FTCD 蛋白, Human (sf9, His)

FTCD 蛋白, Human (sf9, His)

目录号: HY-P76352
COA 产品使用指南

FTCD蛋白是一种叶酸依赖性酶,具有转移酶和脱氨酶活性的双重功能。它在引导甲基亚氨基谷氨酸的一碳单位进入叶酸池方面发挥着至关重要的作用,有助于叶酸代谢的调节。FTCD 蛋白, Human (sf9, His) 是重组的 FTCD 蛋白,由 Sf9 insect cells 表达,带有 C-His 标签。

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规格 价格 是否有货 数量
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5 μg ¥750 In-stock
10 μg ¥1250 In-stock
50 μg ¥3500 In-stock
100 μg   询价  

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The FTCD protein is a folate-dependent enzyme with dual functions of transferase and deaminase activities. It plays a crucial role in directing the one-carbon units from methyliminoglutamic acid into the folate pool, contributing to the regulation of folate metabolism. FTCD Protein, Human (sf9, His) is the recombinant human-derived FTCD protein, expressed by Sf9 insect cells , with C-His labeled tag.

研究背景

FTCD(甲酰亚胺酰转移酶-环脱氨酶)蛋白是一种叶酸依赖性酶,以其多功能性而闻名,具有转移酶和脱氨酶活性。它的主要作用包括将单碳单位从甲亚氨基谷氨酸引导至叶酸库,从而促进重要的细胞过程。此外,FTCD 通过结合并促进源自高尔基体的波形蛋白丝的捆绑而表现出额外的功能。这种在一碳代谢和细胞骨架组织中的双重作用凸显了 FTCD 在细胞稳态中的重要性。所提供的信息基于参考通道,强调了酶参与关键生化途径及其对细胞结构方面的影响。

生物活性

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

种属

Human

表达系统

Sf9 insect cells

标签

C-His

蛋白编号

O95954-1 (M1-E541)

基因 ID
蛋白结构
N-term
FTCD (M1-E541)
Accession # O95954-1
His
C-term
同用名
Formimidoyltransferase-cyclodeaminase; FTCD; LCHC1; Glutamate formyltransferase
氨基酸序列

MSQLVECVPNFSEGKNQEVIDAISGAITQTPGCVLLDVDAGPSTNRTVYTFVGPPECVVEGALNAARVASRLIDMSRHQGEHPRMGALDVCPFIPVRGVSVDECVLCAQAFGQRLAEELDVPVYLYGEAARMDSRRTLPAIRAGEYEALPKKLQQADWAPDFGPSSFVPSWGATATGARKFLIAFNINLLGTKEQAHRIALNLREQGRGKDQPGRLKKVQGIGWYLDEKNLAQVSTNLLDFEVTALHTVYEETCREAQELSLPVVGSQLVGLVPLKALLDAAAFYCEKENLFILEEEQRIRLVVSRLGLDSLCPFSPKERIIEYLVPERGPERGLGSKSLRAFVGEVGARSAAPGGGSVAAAAAAMGAALGSMVGLMTYGRRQFQSLDTTMRRLIPPFREASAKLTTLVDADAEAFTAYLEAMRLPKNTPEEKDRRTAALQEGLRRAVSVPLTLAETVASLWPALQELARCGNLACRSDLQVAAKALEMGVFGAYFNVLINLRDITDEAFKDQIHHRVSSLLQEAKTQAALVLDCLETRQE

分子量

Approximately 60.4 kDa.

纯度

Greater than 90% as determined by reducing SDS-PAGE.

性状

溶液

组分

Supplied as a 0.2 μm filtered solution of 16 mM Hepes, 250 mM NaCl, 20 % glycerol, pH 7.6.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

N/A.

保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

运输条件

Shipping with dry ice.

文件资料

FTCD Protein, Human (sf9, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
FTCD Protein, Human (sf9, His)
目录号:
HY-P76352
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