G-CSF 蛋白, Human (HEK293, Fc)

G-CSF, a pivotal cytokine, regulates hematopoiesis by controlling the production, differentiation, and function of granulocytes and monocytes-macrophages. This monomeric protein specifically promotes granulocyte development, playing a crucial role in immune system regulation and blood cell formation. G-CSF Protein, Human (HEK293, Fc) is the recombinant human-derived G-CSF protein, expressed by HEK293 , with N-hFc labeled tag. The total length of G-CSF Protein, Human (HEK293, Fc) is 174 a.a., with molecular weight of 45-50 kDa.

粒细胞/巨噬细胞集落刺激因子 (G-CSF) 是一种对造血至关重要的细胞因子，控制着两种关键白细胞群的产生、分化和功能：粒细胞和单核细胞-巨噬细胞。作为一种单体蛋白，G-CSF 特异性诱导粒细胞发育，有助于调节免疫系统和血细胞形成。

Immobilized Human G-CSF R, His Tag at 1 μg/mL (100 μl/well) on the plate. Dose response curve for Human G-CSF, hFc Tag with the EC₅₀ of 4.4 ng/mL determined by ELISA.

Human

HEK293

N-hFc

P09919-2/NP_757373.1 (T31-P204)

1440  [NCBI]

TPLGPASSLPQSFLLKCLEQVRKIQGDGAALQEKLCATYKLCHPEELVLLGHSLGIPWAPLSSCPSQALQLAGCLSQLHSGLFLYQGLLQALEGISPELGPTLDTLQLDVADFATTIWQQMEELGMAPALQPTQGAMPAFASAFQRRAGGVLVASHLQSFLEVSYRVLRHLAQP

45-50 kDa

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.