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  3. Galectin-8/LGALS8 蛋白, Rat (GST)

Galectin-8/LGALS8 蛋白, Rat (GST)

目录号: HY-P76943
产品使用指南

半乳糖凝集素-8 (Galectin-8) 属于动物凝集素家族,可结合不同的糖缀合物。Galectin-8 抑制 MTORAMPK 信号通路响应溶酶体损伤诱导自噬。Galectin-8 在多种肿瘤中高表达。Galectin-8/LGALS8 蛋白, Rat (GST) 是重组的 Galectin-8 蛋白,由 E. coli 表达,带有 N-GST 标签。

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描述

Galectin-8 belongs to the family of animal lectins that bind to different glycoconjugates. Galectin-8 inhibits MTOR and AMPK signaling pathways to induce autophagy in response to lysosomal damage. Galectin-8 is highly expressed in a variety of tumors. Galectin-8/LGALS8 Protein, Rat (GST) is the recombinant rat-derived Galectin-8 protein, expressed by E. coli , with N-GST labeled tag.

研究背景

半乳糖凝集素-8 (Galectin-8) 属于动物凝集素家族,可结合不同的糖缀合物。作为一种分泌蛋白,Galectin-8 存在于体液中或乳腺癌患者的血清和结肠癌患者的血清中。细胞外 Galectin-8 通过与细胞粘附分子如整合素 CD44、CD166 和 Podoplanin 结合,促进细胞粘附。Galectin-8 通过标记病原体入侵的空泡被自噬破坏来发挥细胞内功能。在溶酶体损伤引起的膜扰动中,Galectin-8 抑制 MTORAMPK 响应溶酶体损伤诱导自噬。Galectin-8 在多种肿瘤中高表达。

种属

Rat

表达系统

E. coli

标签

N-GST

蛋白编号

Q6IN24 (M1-W316)

基因 ID
蛋白结构
N-term
GST
Galectin-8/LGALS8 (M1-W316)
Accession # Q6IN24
C-term
同用名
Galectin-8; Gal-8; Po66 Carbohydrate-Binding Protein; Po66-CBP; Prostate Carcinoma Tumor Antigen 1; PCTA-1; LGALS8
分子量

Approximately 63.2 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Galectin-8/LGALS8 Protein, Rat (GST) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Galectin-8/LGALS8 Protein, Rat (GST)
目录号:
HY-P76943
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