2. 重组蛋白
  3. Cytokines and Growth Factors Biotinylated Proteins
  4. TGF-beta Superfamily Neurotrophic Factors
  5. TGF-β TGF-β
  6. TGF-β1
  7. GARP&Latent TGF Beta 1 Complex 蛋白, Human (HEK293, His-Avi)

GARP&Latent TGF Beta 1 Complex 蛋白, Human (HEK293, His-Avi)

目录号: HY-P700865
产品使用指南

GARP 是一种跨膜蛋白，是潜在转化生长因子 (LTGF-β) 的对接受体，在活性转化生长因子 β (TGF-β) 的产生和释放中起关键作用。GARP 的存在影响免疫介导的疾病，如癌症、过敏和自身免疫。GARP&Latent TGF Beta 1 Complex 蛋白, Human (HEK293, His-Avi) 是重组的蛋白二聚体复合物，包含 GARP&潜在 TGF Beta 1 复合蛋白，由 HEK293 表达，带有 C-Avi, C-His 标签。GARP&Latent TGF Beta 1 Complex 蛋白, Human (HEK293, His-Avi) ，分子量分别为 70-80 kDa (GARP) & 42-48 kDa & 13 kDa (L。

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100 μg   询价  

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描述

GARP is a transmembrane protein that acts as a docking receptor for potential transforming growth factor (LTGF-β) and plays a key role in the production and release of active transforming growth factor β (TGF-β). The presence of GARP affects immune-mediated diseases such as cancer, allergies, and autoimmunity. GARP&Latent TGF Beta 1 Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing rat-derived GARP&Latent TGF Beta 1 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. GARP&Latent TGF Beta 1 Complex Protein, Human (HEK293, His-Avi), has molecular weight of 70-80 kDa (GARP) & 42-48 kDa & 13 kDa (L, respectively.
研究背景

GARP 是一种跨膜蛋白，是潜在转化生长因子 (LTGF-β) 的对接受体，在活性转化生长因子 β (TGF-β) 的产生和释放中起关键作用。GARP 作为可溶性因子和不同细胞类型的表面标记物的存在影响免疫介导的疾病，如癌症、过敏和自身免疫。GARP 可以作为生物标志物和治疗靶点。
种属

Rat
表达系统

HEK293
标签

C-Avi;C-His
蛋白编号

D3ZVD5 (I18-N628)&P17246 (L30-R278)
基因 ID

293135&59086
同用名
LRRC32; GARP; LAP; TGF-beta-1; LRRC32&TGF-beta 1; LRRC32&TGFB1; TGF-β-1; LRRC32&TGF-β 1; GARP&Latent TGF Beta; GARP&Latent TGF Beta 1
分子量

70-80 kDa (GARP) & 42-48 kDa & 13 kDa (L
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

GARP&Latent TGF Beta 1 Complex Protein, Human (HEK293, His-Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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