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  4. GLTP 蛋白, Human (HEK293, His)

GLTP 蛋白, Human (HEK293, His)

目录号: HY-P76365
产品使用指南

GLTP 蛋白对于促进多种糖脂的膜间转移至关重要，特别是催化多种鞘糖脂的转移，同时排除磷脂。它在葡萄糖神经酰胺细胞内易位中的潜在作用强调了它在脂质代谢中的重要性。值得注意的是，GLTP 作为单体执行这些脂质转移活动。GLTP 蛋白, Human (HEK293, His) 是重组的 GLTP 蛋白，由 HEK293 表达，带有 N-His 标签。GLTP 蛋白, Human (HEK293, His) 全长 209 个氨基酸，分子量约为 ~26.2 KDa。

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描述

GLTP Protein is pivotal in facilitating the intermembrane transfer of diverse glycolipids, specifically catalyzing the transfer of various glycosphingolipids while excluding phospholipids. Its potential role in intracellular translocation of glucosylceramides underscores its significance in lipid metabolism. Notably, GLTP operates as a monomer in executing these lipid transfer activities. GLTP Protein, Human (HEK293, His) is the recombinant human-derived GLTP protein, expressed by HEK293 , with N-His labeled tag. The total length of GLTP Protein, Human (HEK293, His) is 209 a.a., with molecular weight of ~26.2 KDa.
研究背景

GLTP蛋白在促进多种糖脂的膜间转移中发挥着至关重要的作用。具体来说，它催化各种鞘糖脂在膜之间的转移，其特点是在转移过程中排除了磷脂。该蛋白质可能参与葡萄糖神经酰胺的细胞内易位，进一步强调了其在脂质代谢中的重要性。值得注意的是，GLTP 在执行这些脂质转移活动中充当单体。
种属

Human
表达系统

HEK293
标签

N-His
蛋白编号

Q9NZD2 (M1-V209)
基因 ID
蛋白结构
N-term
His
GLTP (M1-V209)
Accession # Q9NZD2
C-term
同用名
Glycolipid transfer protein; GLTP
分子量

Approximately 26.2 kDa.
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

GLTP Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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