GMF-beta 蛋白, Mouse

GMF-β protein is a multifaceted regulatory factor that coordinates brain cell differentiation, stimulates neuroregeneration, and inhibits tumor cell proliferation. Phosphorylation initiated by phorbol esters is critical for its activity, suggesting a dynamic regulatory mechanism in response to external signals. GMF-beta Protein, Mouse is the recombinant mouse-derived GMF-beta protein, expressed by E. coli , with tag free. The total length of GMF-beta Protein, Mouse is 141 a.a., with molecular weight of ~19.7 kDa.

GMF-β 蛋白作为多方面的调节剂出现，协调脑细胞的分化，刺激神经再生，同时抑制肿瘤细胞的增殖。这种多功能蛋白质会经历磷酸化，这是一种对其活性至关重要的修饰，尤其是由佛波酯触发。GMF-β 的磷酸化状态表明了一种响应外部信号的动态调节机制，可能在细胞信号级联中发挥关键作用。凭借其影响神经发育和阻碍肿瘤细胞增殖的双重能力，GMF-β 在细胞命运和功能的复杂调节中发挥着关键作用，有望进一步探索理解和操纵这些基本生物过程。

Mouse

E. coli

Tag Free

Q9CQI3 (S2-H142)

63985  [NCBI]

SESLVVCDVAEDLVEKLRKFRFRKETHNAAIIMKIDKDERLVVLDEELEGVSPDELKDELPERQPRFIVYSYKYQHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNKLVQTAELTKVFEIRNTEDLTEEWLREKLGFFH

Approximately 19.7 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg; determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.