2. 重组蛋白
  3. Enzymes & Regulators
  4. Lyases (EC 4)
  5. GUCY2C/Guanylyl cyclase C 蛋白, Human (HEK293, Fc)

GUCY2C/Guanylyl cyclase C 蛋白, Human (HEK293, Fc)

目录号: HY-P77942
产品使用指南

GUCY2C 是一种鸟苷酸环化酶，催化 GTP 合成 cGMP，并作为大肠杆菌热稳定肠毒素的受体，刺激表达哺乳动物细胞中 cGMP 的积累。此外，内源性肽鸟苷蛋白和尿鸟苷蛋白可激活 GUCY2C。研究证实，这种多方面的作用强调了细胞信号传导中复杂的调节机制以及 GUCY2C 对各种刺激的反应。GUCY2C/Guanylyl cyclase C 蛋白, Human (HEK293, Fc) 是重组的 GUCY2C/鸟苷酸环化酶 C 蛋白，由 HEK293 表达，带有 C-hFc 标签。GUCY2C/Guanylyl cyclase C 蛋白, Human (HEK293, Fc) 全长 407 个氨基酸，分子量为 85-115 kDa。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

GUCY2C, a guanylyl cyclase, catalyzes cGMP synthesis from GTP and acts as a receptor for E. coli heat-stable enterotoxin, stimulating cGMP accumulation in expressing mammalian cells. Additionally, endogenous peptides guanylin and uroguanylin activate GUCY2C. This multifaceted role underscores intricate regulatory mechanisms in cellular signaling and GUCY2C's responsiveness to various stimuli, as confirmed by studies. GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, Fc) is the recombinant human-derived GUCY2C/Guanylyl cyclase C protein, expressed by HEK293 , with C-hFc labeled tag. The total length of GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, Fc) is 407 a.a., with molecular weight of 85-115 kDa.
研究背景

研究证明，GUCY2C 是一种鸟苷酸环化酶，可作为 GTP 合成环 (cGMP) 的催化剂。此外，该蛋白还充当大肠杆菌热稳定肠毒素的受体，其中肠毒素显着刺激表达 GUCY2C 的 cin 哺乳动物细胞的积累。此外，GUCY2C 被内源性肽、鸟苷蛋白和尿鸟苷蛋白激活。这种多方面的作用强调了细胞信号传导中涉及 GUCY2C 的复杂调节机制及其对各种刺激的反应。
种属

Human
表达系统

HEK293
标签

C-hFc
蛋白编号

P25092 (S24-Q430)
基因 ID
蛋白结构
N-term
GUCY2C (S24-Q430)
Accession # P25092
hFc
C-term
同用名
Guanylyl cyclase C; GC-C; STAR; GUCY2C; GUC2C; STA receptor; DIAR6; EC 4.6.1; GCC; GUC2CEC 4.6.1.2; MUCIL
分子量

85-115 kDa
纯度

Greater than 95% as determined by Tris-Bis PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
GUCY2C/Guanylyl cyclase C Protein, Human (HEK293, Fc)
目录号：
HY-P77942
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z