IGFL1 蛋白, Human (HEK293, hFc)

The IGFL1 protein is a possible ligand of the IGFLR1 receptor and mediates cellular responses through receptor binding. As a homodimer with disulfide bonds, the structural arrangement of IGFL1 suggests involvement in specific signaling events. IGFL1 Protein, Human (HEK293, hFc) is the recombinant human-derived IGFL1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IGFL1 Protein, Human (HEK293, hFc) is 86 a.a., with molecular weight of 42 kDa.

IGFL1 蛋白被鉴定为 IGFLR1 细胞膜受体的可能配体，表明其通过受体结合介导细胞反应的作用。IGFL1 作为具有二硫键的同型二聚体存在，其结构排列表明其在与其同源受体结合后可能参与特定的信号转导事件。IGFL1 的同二聚体性质强调了其复杂相互作用的能力，强调了其在 IGFLR1 受体介导的细胞通讯和信号通路中的潜在重要性。对 IGFL1-IGFLR1 相互作用的精确机制和下游效应的进一步研究将为了解该配体-受体对的功能作用提供有价值的见解。

Measured by its binding ability in a functional ELISA. Immobilized Human IGFLR1 at 5 μg/mL can bind IGFL1 Protein, Human (HEK293, hFc), the EC₅₀ is ≤ 55 ng/mL.

Human

HEK293

C-hFc

Q6UW32 (A25-S110)

374918  [NCBI]

APVAPMTPYLMLCQPHKRCGDKFYDPLQHCCYDDAVVPLARTQTCGNCTFRVCFEQCCPWTFMVKLINQNCDSARTSDDRLCRSVS

42 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, 6% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.