1. Gene
  2. IGFL1 - IGF like family member 1 Gene

IGFL1 - IGF like family member 1 Gene

中文名称:IGF 样家族成员 1

种属: Homo sapiens

同用名: UNQ644; APRG644

基因 ID: 374918 | 基因类型: protein coding

关于 IGFL1

Cytogenetic location: 19q13.32 Genomic coordinates (GRCh38): 19:46,229,742-46,231,243 (from NCBI)

This gene has 1 transcript (splice variant), 47 orthologues and 3 paralogues. Restricted expression toward esophagus (RPKM 30.9).

功能概要

该基因编码的蛋白质是胰岛素样生长因子信号分子家族的成员。编码的蛋白质被合成为前体蛋白质,并被蛋白水解切割以形成分泌的成熟肽。成熟的肽与受体结合,在小鼠中发现该受体存在于 T 细胞的细胞表面。该基因表达增加可能与牛皮癣有关。[RefSeq 提供,2016 年 8 月]

The protein encoded by this gene is a member of the insulin-like growth factor family of signaling molecules. The encoded protein is synthesized as a precursor protein and is proteolytically cleaved to form a secreted mature peptide. The mature peptide binds to a receptor, which in mouse was found on the cell surface of T cells. Increased expression of this gene may be linked to psoriasis. [provided by RefSeq, Aug 2016]

IGFL1 基因产物(1)

mRNA Protein Name
NM_198541.2 NP_940943.1 insulin growth factor-like family member 1 precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21454693 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
21454693 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

IGFL1 蛋白结构

IGFL

IGFL: Insulin growth factor-like family (27 - 89)

  • 0
  • 100
  • 110 a.a.
蛋白主名 其他名称

insulin growth factor-like family member 1

重组 IGFL1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P700450 IGFL1 Protein, Human (HEK293, hFc) Q6UW32 (A25-S110) ≥95%

直系同源

种属 基因名 来源 基因 ID
Mus musculus IGFL1 NCBI