1. 重组蛋白
  2. Cytokines and Growth Factors
  3. IGF family
  4. IGFL2 蛋白, Human (HEK293, N-hFc)

IGFL2 蛋白, Human (HEK293, N-hFc)

目录号: HY-P77395A
COA 产品使用指南

IGFL2 蛋白作为 IGFLR1 细胞膜受体的潜在配体出现,表明其在介导细胞信号传导事件中发挥作用。作为一种假定的配体,IGFL2 已准备好与 IGFLR1 受体相互作用,表明其参与细胞反应和信号级联反应。IGFL2 蛋白, Human (HEK293, N-hFc) 是重组的 IGFL2 蛋白,由 HEK293 表达,带有 N-hFc 标签。IGFL2 蛋白, Human (HEK293, N-hFc) 全长 94 个氨基酸

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10 μg ¥1000 In-stock
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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The IGFL2 protein emerged as a potential ligand for the IGFLR1 cell membrane receptor, suggesting a role in mediating cell signaling events. As a putative ligand, IGFL2 is primed to interact with the IGFLR1 receptor, suggesting involvement in cellular responses and signaling cascades. IGFL2 Protein, Human (HEK293, N-hFc) is the recombinant human-derived IGFL2, expressed by HEK293 , with N-hFc labeled tag. The total length of IGFL2 Protein, Human (HEK293, N-hFc) is 94 a.a.,

研究背景

IGFL2 蛋白作为 IGFLR1 细胞膜受体的潜在配体出现,表明在介导细胞信号传导事件中具有潜在作用。作为一种假定的配体,IGFL2 准备与细胞膜上的 IGFLR1 受体相互作用,表明参与细胞反应和信号级联反应。IGFL2 作为潜在配体的鉴定强调了其在细胞通讯和调控过程中的重要性,强调需要进一步探索以揭示 IGFL2 在各种细胞环境中可能发挥的特定分子相互作用和功能。

生物活性

Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human IGFLR1 at 2 µg/mL can bind Human IGFL2. The ED50 for this effect is 1.811 μg/mL.

  • Measured by its binding ability in a functional ELISA. Immobilized Recombinant Human IGFLR1 at 2 µg/mL can bind Human IGFL2. The ED50 for this effect is 1.811 μg/mL..
种属

Human

表达系统

HEK293

标签

N-hFc

蛋白编号

Q6UWQ7-1 (P26-P119)

基因 ID

147920

同用名
Insulin growth factor-like family member 2; IGFL2
氨基酸序列

PAGSEPWLCQPAPRCGDKIYNPLEQCCYNDAIVSLSETRQCGPPCTFWPCFELCCLDSFGLTNDFVVKLKVQGVNSQCHSSPISSKCESRRRFP

分子量

Approximately 40 kDa

纯度
  • Greater than 95% as determined by reducing SDS-PAGE.
性状

无菌粉末

组分

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料

IGFL2 Protein, Human (HEK293, N-hFc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
IGFL2 Protein, Human (HEK293, N-hFc)
目录号:
HY-P77395A
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