2. 重组蛋白
  3. Fc Receptors
  4. Immunoglobulin Fc Region
  5. IgG2C
  6. IgG2C Fc 蛋白, Mouse (HEK293)

IgG2C Fc 蛋白, Mouse (HEK293)

目录号: HY-P700737
COA 产品使用指南

IgG2C Fc 是 IgG2 的一个亚类。小鼠 IgG2c Fc 环残基比小鼠 IgG2b 或人 IgG1 具有更强的受体结合亲和力。IgG2C Fc 蛋白, Mouse (HEK293) 是重组的 IgG2C Fc 蛋白，由 HEK293 表达，不带标签。IgG2C Fc 蛋白, Mouse (HEK293) 全长 234 个氨基酸，分子量为 30-40 kDa。

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规格 价格 是否有货 数量
20 μg ￥550 In-stock
50 μg ￥1050 In-stock
100 μg ￥1650 询价
> 100 μg   询价  

* Please select Quantity before adding items.

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描述

IgG2C Fc is a subclass of IgG2. Mouse IgG2c Fc loop residues have stronger receptor binding affinity than mouse IgG2b or human IgG1. IgG2C Fc Protein, Mouse (HEK293) is the recombinant mouse-derived IgG2C Fc protein, expressed by HEK293 , with tag free. The total length of IgG2C Fc Protein, Mouse (HEK293) is 234 a.a., with molecular weight of 30-40 kDa.
研究背景

抗体通过多种不同的机制保护病原体和病变组织免受入侵，包括中和作用、抗体依赖细胞介导的细胞毒性 (ADCC)、补体介导的细胞毒性、吞噬作用和噬细胞作用。小鼠菌株表达三个 IgG2 亚类:IgG2a、2b 和 2c。小鼠 IgG2c Fc 环残基比小鼠 IgG2b 或人 IgG1 促进更强的受体结合亲和力。
种属

Mouse
表达系统

HEK293
标签

Tag Free
蛋白编号

F6TQW2 (I97-S330)
基因 ID

/
蛋白结构
N-term
IgG2C Fc (I97-S330)
Accession # F6TQW2
C-term
同用名
Ighg2c; IgG2C
分子量

30-40 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
性状

无菌粉末.
组分

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.
内毒素含量

<1 EU/μg, determined by LAL method.
复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.
保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
运输条件

Room temperature in continental US; may vary elsewhere.
文件资料

COA (147 KB)

产品使用指南 (1213 KB)

IgG2C Fc Protein, Mouse (HEK293) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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目录号：
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