1. 重组蛋白
  2. Cytokines and Growth Factors CD Antigens Receptor Proteins
  3. Interleukin & Receptors B Cell CD Proteins NK Cell CD Proteins Cytokine Receptors
  4. IL-21R IL-21R
  5. IL-21R 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc)

IL-21R 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc)

目录号: HY-P76431
产品使用指南

Interleukin-21 receptor 是一种新型的I类细胞因子受体,它通过与共同的 g链 (gc) 相互作用来介导其效应,使 IL-21 成为包括 IL-2、IL-4、IL-7、IL-9、IL-13 和 IL-15在内的 gc 细胞因子家族的最新成员。IL-21R 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc) 是重组的 IL-21R 蛋白,由 HEK293 表达,带有 C-hFc 标签。IL-21R 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc) 全长 236 个氨基酸,分子量约为 ~52 KDa。

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描述

Interleukin-21 receptor is a novel class I cytokine receptor that mediates its effects through the interaction with the common g chain (gc), making IL-21 the latest member of the family of gc cytokines, which includes IL-2, IL-4, IL-7, IL-9, IL-13, and IL-15. IL-21R Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived IL-21R protein, expressed by HEK293 , with C-hFc labeled tag.

研究背景

Interleukin-21 receptor 是一种新型的I类细胞因子受体,它通过与共同的 g链 (gc) 相互作用来介导其效应,使 IL-21 成为包括 IL-2、IL-4、IL-7、IL-9、IL-13 和 IL-15在内的 gc 细胞因子家族的最新成员。Interleukin-21 receptor 激活细胞因子受体活性和蛋白结合。Interleukin-21 receptor 参与细胞因子介导的信号通路和免疫球蛋白介导的免疫应答。Interleukin-21 receptor 位于质膜外侧[1][2][3]

种属

Rhesus Macaque

表达系统

HEK293

标签

C-hFc

蛋白编号

XP_005591578 (C20-P236)

基因 ID
蛋白结构
N-term
IL-21R (C2-P236)
Accession # XP_5591578
hFc
C-term
同用名
Interleukin-21 receptor; IL-21 receptor; IL-21R; CD360; Nilr
分子量

Approximately 52 kDa.

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

IL-21R Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
IL-21R Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc)
目录号:
HY-P76431
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