IL-22 蛋白, Cynomolgus (HEK293, His)

IL-22 Protein, a member of the IL-10 family, stands out for its divergence. This crucial cytokine plays a central role in immune responses and inflammation. IL-22 promotes activation and recruitment of immune cells like Th2 cells, mast cells, and eosinophils to inflammation sites. Primarily secreted by epithelial and endothelial cells, IL-22 acts through its receptor, stimulating the production of pro-inflammatory cytokines and chemokines. Implicated in diseases like asthma, allergies, and autoimmune disorders, IL-22 holds promise as a therapeutic target for immune response modulation. IL-22 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-22 protein, expressed by HEK293, with C-His labeled tag. The total length of IL-22 Protein, Cynomolgus (HEK293, His) is 146 a.a., with molecular weight of 32-42 kDa.

IL-22 蛋白属于 IL-10 家族，因其与其他家族成员的显着差异而闻名。这种蛋白质作为重要的细胞因子参与多种免疫反应和炎症过程。IL-22 在促进免疫细胞（包括辅助性 T 2 (Th2) 细胞、肥大细胞和嗜酸性粒细胞）激活和募集至炎症部位方面发挥着至关重要的作用。它主要由上皮细胞和内皮细胞分泌，通过IL-22受体发挥作用。结合后，IL-22 会刺激各种促炎细胞因子和趋化因子的产生。值得注意的是，IL-22 与多种疾病有关，例如哮喘、过敏性疾病和自身免疫性疾病，强调了其作为调节免疫反应的潜在治疗靶点的重要性。

Cynomolgus

HEK293

C-His

G7PHZ7 (A34-I179)

102129310  [NCBI]

32-42 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.