2. 重组蛋白
  3. Cytokines and Growth Factors Receptor Proteins
  4. Interleukin & Receptors Cytokine Receptors
  5. IL-23 Receptor
  6. IL-23R 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc)

IL-23R 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc)

目录号: HY-P75857
产品使用指南

Interleukin 23 receptor 是 IL23A/IL23 受体的一个亚单位。Interleukin 23 receptor 与 Janus 激酶 2 (JAK2) 组成性结合，也以配体依赖的方式与转录激活因子 STAT3 结合。IL-23R 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc) 是重组的 IL-23R 蛋白，由 HEK293 表达，带有 C-hFc 标签。IL-23R 蛋白, Cynomolgus/Rhesus Macaque (HEK293, Fc) 全长 353 个氨基酸，分子量约为 ~64.9 kDa。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

SPR 检测服务   重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

Interleukin 23 receptor is a subunit of the receptor for IL23A/IL23. Interleukin 23 receptor associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. IL-23R Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived IL-23R protein, expressed by HEK293 , with C-hFc labeled tag. The total length of IL-23R Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) is 353 a.a., with molecular weight of ~64.9 kDa.
研究背景

Interleukin 23 receptor 是 IL23A/IL23 受体的一个亚单位。Interleukin 23 receptor 与受体分子 IL12RB1/ il12rbet1 配对，两者均为 IL23A 信号传导所必需。Interleukin 23 receptor 与 Janus 激酶 2 (JAK2) 组成性结合，也以配体依赖的方式与转录激活因子 STAT3 结合。Interleukin 23 receptor 促进白细胞介素-12 受体结合并促进白细胞介素-23 受体活性。Interleukin 23 receptor 参与对革兰氏阴性菌的防御反应和 T 细胞增殖的正向调节[1][2][3][4][5]。
种属

Rhesus Macaque
表达系统

HEK293
标签

C-hFc
蛋白编号

F6XR82 (M1-D353)
基因 ID

/
蛋白结构
N-term
IL-23R (M1-D353)
Accession # F6XR82
hFc
C-term
同用名
Interleukin 23 receptor; IL 23R; IL-23 receptor; IL-23R
分子量

Approximately 64.9 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

IL-23R Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
IL-23R Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc)
目录号：
HY-P75857
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z