Inhibin alpha chain/INHA 蛋白, Bovine (His-SUMO)

Inhibin alpha chain/INHA protein plays a vital role in regulating pituitary function and contributes to the dual regulation of follicle-stimulating hormone secretion and activin. Inhibin alpha chain/INHA Protein, Bovine (His-SUMO) is the recombinant bovine-derived Inhibin alpha chain/INHA protein, expressed by E. coli , with N-His, N-SUMO labeled tag. The total length of Inhibin alpha chain/INHA Protein, Bovine (His-SUMO) is 134 a.a., with molecular weight of ~33 kDa.

抑制素 α 链/INHA 蛋白在垂体功能的复杂调节中占据中心地位，与激活素一起参与促卵泡素分泌的双重调节。抑制素和激活素（其中抑制素 A 是关键成分）的更广泛影响涵盖多种生理过程，包括下丘脑和垂体激素分泌、性腺激素分泌、生殖细胞发育和成熟、红细胞分化、胰岛素分泌、神经细胞存活、胚胎轴发育和骨骼生长，取决于它们的亚基组成。值得注意的是，以抑制素 A 为代表的抑制素在这个多方面的调节网络中作为激活素功能的明显拮抗剂出现。在结构上，抑制素 A 以二聚体形式存在，通过一个或多个二硫键错综复杂地连接，其亚基组成包含 α 和 β-A 亚基。这种二聚体结构强调了抑制素 A 作用的复杂性，揭示了它参与多种生理功能的精细协调。

Bovine

E. coli

N-His;N-SUMO

P07994 (S227-I360)

281254  [NCBI]

STPPLPWPWSPAALRLLQRPPEEPAAHADCHRAALNISFQELGWDRWIVHPPSFIFYYCHGGCGLSPPQDLPLPVPGVPPTPVQPLSLVPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYEMVPNLLTQHCACI

Approximately 33 kDa

• 
  Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.